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Iranian Journal of Dermatology، جلد ۲۳، شماره ۴، صفحات ۱۵۰-۱۵۴
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Frequency of depression in patients with acne vulgaris treated with short-course low dose oral isotretinoin |
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| چکیده انگلیسی مقاله |
Introduction: Acne vulgaris affects individuals of all ages, and isotretinoin is the most effective treatment available for this disease. However, serious adverse effects, including the possibility of depression and suicide, could limit its use. This study aimed to investigate the frequency of depression in patients with acne vulgaris treated with oral isotretinoin.
Materials and Methods: Forty acne vulgaris patients treated with oral isotretinoin and 40 age- and sex-matched controls treated with a systemic antibiotic (doxycycline 100-200 mg/day) and a
topical retinoid were enrolled in this study. The depression score was measured based on Beck’s Depression Inventory (BDI) in both groups before and after two months of treatment.
Result: The BDI score and the rate of depression were not significantly different between the two groups after the twomonth treatment period. Moreover, we did not find any significant change in BDI score in each group after treatment (P > 0.05).
Conclusion: Our study showed that short-course oral isotretinoin therapy does not increase the depression rate among acne vulgaris patients. It should be noted that oral isotretinoin causes
a significant clinical improvement in patients with moderate to severe acne vulgaris, which could be associated with a decrease in depression scores.
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| کلیدواژه‌های انگلیسی مقاله |
depression,Acne Vulgaris,Isotretinoin |
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| نویسندگان مقاله |
Nasim Niknezhad |
Skin Research Center, Shohada-e Tajrish Hospital, ShahidBeheshti University of Medical Sciences, Tehran, Iran
Behnaz Hamedani |
Skin Research Center, Shohada-e Tajrish Hospital, ShahidBeheshti University of Medical Sciences, Tehran, Iran
Abbas Zamanian |
Department of Dermatology, Iran University of Medical Sciences, Tehran, Iran
Reza Mahmoud Robati |
Skin Research Center, Shohada-e-
Tajrish Hospital, Shahid Beheshti
University of Medical Sciences,
Tehran, Iran
Elnaz Hamedani |
Department of Nursing, Islamic Azad University, Tehran, Iran
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| نشانی اینترنتی |
https://www.iranjd.ir/article_120834_5f9b7b99b05edbfe66f904847655e48d.pdf |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
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| نوع مقاله منتشر شده |
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