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مجله بین المللی کودکان و نوجوانان، جلد ۱، شماره ۱، صفحات ۱۰-۱۳
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| عنوان انگلیسی |
Fibronectin in reflux nephropathy Is it a marker of reflux grade? |
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| چکیده انگلیسی مقاله |
Background and Objective: Vesicoureteral reflux (VUR) is one of the most common urinary tract abnormalities in patients with urinary tract infection. Nowadays noninvasive diagnostic methods are suggested to recognize VUR and its severity. Methods: We measured urinary and serum fibronectin in 51 children with VUR. Results: The mean serum fibronectin was 318.3±112.1 in children with low grade VUR versus 356.1±189.9 in children with high grade VUR (p>0.05). The mean urinary fibronectin was also 31.5±12.9 in low grade VUR and 25.9±14.2 in high grade VUR (p>0.05). Thus we found no association between the severity of VUR and the amount of fibronectin in serum and urine of patients. We also f found no relationship between dimercaptosuccinic acid (DMSA) changes at the acute phase of unitary tract infection (UTI) and serum and urine fibronectin. Conclusion: Contrary to some previous studies, we showed the serum and urinary fibronectin cannot preclude the severity and grade of VUR and hence it is not suitable surrogate marker for imaging techniques for VUR diagnosis. |
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| نویسندگان مقاله |
ناهید رحیم زاده | nahid rahimzadeh
pediatric transplantation and dialysis research center
مرسده قدسی | mersedeh ghodsi
مینا ترک زبان | mina torkzaban
labafi nejad hospital
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| نشانی اینترنتی |
http://ijca.iums.ac.ir/browse.php?a_code=A-10-1-3&slc_lang=en&sid=en |
| فایل مقاله |
اشکال در دسترسی به فایل - ./files/site1/rds_journals/1929/article-1929-290720.pdf |
| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
تخصصی |
| نوع مقاله منتشر شده |
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