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مجله بین المللی کودکان و نوجوانان، جلد ۱، شماره ۲، صفحات ۲۵-۲۸
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Beta trace protein as GFR marker in children |
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| چکیده انگلیسی مقاله |
Background and Objective: Serum creatinine is the most used endogenous marker of glomerular filtration rate (GFR), but it also has multiple limitations. Therefore, some surrogate GFR markers, such as beta trace protein, have been introduced for GFR estimation. The aim of our study was to estimate GFR by serum beta trace protein using three available equations and compare them to DTPA GFR as the gold standard and Schwartz GFR. Methods: The three beta trace protein (BTP)-related GFR formulas were the White formula (1): GFR=167.8×BTP-0.758×creatinine-0.204, Pöge formula (2): GFR=974.31×BTP-0.2594×creatinine-0.647, and Benlamri formula (3): GFR=10^ (1.902+ (0.9515×LOG (1/BTP)). Twenty seven children were included in this study. All patients had a Schwartz and DTPA GFR more than 50 cc/min/1.73m2. Results: We showed that there was no significant correlation between DTPA GFR and Schwartz-estimated GFR (r= -0.1, Pv= 0.5). There also was not any association between GFR estimated by Pöge and Benlamri formulas and DTPA scans. In contrast, there was a significant association between DTPA GFR and White BTP formula-estimated GFR (r=0.77 r=0.00). Conclusion: This study showed that GFR estimated by serum beta trace protein and White formula had accuracy over Schwartz formula in children with normal or mild reduced GFR however, this result needs to be confirmed by additional studies with more cases. |
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| کلیدواژه‌های انگلیسی مقاله |
Beta trace protein, GFR marker, Children |
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| نویسندگان مقاله |
راما naghshizadian | rama naghshizadian
pediatric nephrologist, pediatric transplantation and dialysis research center, iran university of medical sciences, tehran, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)
سپیده حکمت | sepideh hekmat
radionuclide scan specialist, pediatric transplantation and dialysis research center, iran university of medical sciences, tehran, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)
nakyssa هومن | nakyssa hooman
pediatric nephrologist, pediatric transplantation and dialysis research center, iran university of medical sciences, tehran, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)
ناهید رحیم زاده | nahid rahimzadeh
pediatric nephrologist, pediatric transplantation and dialysis research center, iran university of medical sciences, tehran, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)
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| نشانی اینترنتی |
http://ijca.iums.ac.ir/browse.php?a_code=A-10-1-15&slc_lang=en&sid=en |
| فایل مقاله |
اشکال در دسترسی به فایل - ./files/site1/rds_journals/1929/article-1929-290716.pdf |
| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
تخصصی |
| نوع مقاله منتشر شده |
پژوهشی |
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