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Middle East Journal of Digestive Diseases، جلد ۱۵، شماره ۳، صفحات ۲۰۳-۲۰۶
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Serum Albumin Levels Relation to Tumor Aggressiveness in Patients with Hepatocellular Carcinoma from a Tertiary Care Hospital in Pakistan |
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| چکیده انگلیسی مقاله |
Background Hepatocellular carcinoma (HCC) is a major cause of morbidity and mortality in patients with chronic liver diseases. Studies have shown a correlation between low serum albumin levels and the aggressiveness of liver cancer. We aimed to determine the prevalence of hypoalbuminemia and its relationship with HCC aggressiveness in our patients. Methods This study was conducted retrospectively, and data were gathered from the gastroenterology unit of the Department of Medicine at the Aga Khan University Hospital in Karachi, Pakistan.The study included all patients who had been diagnosed with HCC between February 2015 and February 2019. Results In total, 380 patients with HCC were included in this study.The mean serum albumin level was 2.79 g/dL (SD±0.655) and 318 (83.7%) had serum albumin levels of ≤ 3.5 g/dL.No statistically significant association was identified between albumin levels and parameters of tumor aggressiveness (tumor size, number of tumor nodules, portal vein thrombosis, and alpha-fetoprotein levels) in our patients. Conclusion We found no association between low albumin levels and parameters of HCC progression in our patients. This highlights the need for additional markers to determine the severity of hepatocellular carcinoma in underdeveloped populations. |
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| کلیدواژه‌های انگلیسی مقاله |
Serum albumin, Hepatocellular carcinoma, Developingcountry |
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| نویسندگان مقاله |
| Mahrukh Ali
Aga Khan University Hospital Karachi
| Om Parkash
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| نشانی اینترنتی |
http://mejdd.org/index.php/mejdd/article/view/2706 |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
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| نوع مقاله منتشر شده |
Original Article |
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