Current Medical Mycology، جلد ۱، شماره ۱، صفحات ۴۲-۴۸
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عنوان انگلیسی Pneumocystis jirovecii colonization in Chronic Obstructive Pulmonary Disease (COPD)
چکیده انگلیسی مقاله Chronic obstructive pulmonary disease (COPD) is associated with a chronic inflammatory response in airways and lung parenchyma that results in significant morbidity and mortality worldwide. Cigarette smoking considered as an important risk factor plays a role in pathogenesis of disease. Pneumocystis jirovecii is an atypical opportunistic fungus that causes pneumonia in immunosuppressed host, although the low levels of its DNA in patients without signs and symptoms of pneumonia, which likely represents colonization. The increased prevalence of P. jirovecii colonization in COPD patients has led to an interest in understanding its role in the disease. P. jirovecii colonization in these patients could represent a problem for public health since colonized patients could act as a major reservoir and source of infection for susceptible subjects. Using sensitive molecular techniques, low levels of P. jirovecii DNA have been detected in the respiratory tract of certain individuals. It is necessary to elucidate the role of P. jirovecii colonization in the natural history of COPD patients in order to improve the clinical management of this disease. In the current review paper, we discuss P. jirovecii colonization in COPD patients.
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نویسندگان مقاله صادق خداویسی | sadegh khodavaisy
department of medical parasitology and mycology, kurdistan university of medical sciences, sanandaj, iran


اسماعیل مرتاض | esmaeil mortaz
division of pharmacology, utrecht institute for pharmaceutical sciences, faculty of science, utrecht university, utrecht, the netherlands.


فایزه محمدی | faezeh mohammadi
department of medical parasitology and mycology, school of public health, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

مسعود علیالی | masoud aliyali
pulmonary and critical care division, mazandaran university of medical sciences, sari, iran;

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مازندران (Mazandaran university of medical sciences)

حامد فخیم | hamed fakhim
department of medical mycology and parasitology, school of medicine mazandaran university of medical sciences, sari, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مازندران (Mazandaran university of medical sciences)

حمید بدلی | hamid badali
department of medical mycology and parasitology invasive fungi research center, school of medicine mazandaran university of medical sciences, sari, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مازندران (Mazandaran university of medical sciences)

نشانی اینترنتی http://cmm.mazums.ac.ir/browse.php?a_code=A-10-105-16&slc_lang=en&sid=en
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/1790/article-1790-282525.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده قارچ شناسی پزشکی
نوع مقاله منتشر شده مقاله مروری
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