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Veterinary Research Forum، جلد ۷، شماره ۴، صفحات ۳۴۳-۳۴۷
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عنوان فارسی |
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چکیده فارسی مقاله |
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کلیدواژههای فارسی مقاله |
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عنوان انگلیسی |
Effect of soy milk on circulating 17- β estradiol, number of neurons in cerebral cortex and hippocampus and determination of their ratio in neonatal ovariectomized rats |
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چکیده انگلیسی مقاله |
This study was conducted to evaluate the effect of soy milk on serum 17- β estradiol level and number of neurons in cerebral cortex and hippocampus as well as determination of the ratio of neurons in cortical and hippocampal regions in neonatal ovariectomized rats. Thirty female rats (one day old) were divided into six groups of five. At day 7, ovariectomy surgery was performed in four groups and two other groups were assumed as sham and control groups. Three groups of ovareictomaized rats were fed with soy milk at the doses of 0.75, 1.50 and 3.00 mL kg-1 per day since they were 14. At day 60, the blood samples were collected to measure the17- β estradiol concentration, and then the brain of rats were prepared for histological studies. The serum 17- β estradiol level significantly increased in ovariectomized rats fed with soy milk compared to ovariectomized rats with no soy milk supplementation. In addition, the results showed that soy milk significantly increased the number of neurons in CA1, CA2 and dentate gyrus regions of hippocampus and granular layer of cerebral cortex in ovariectomized rats, whereas there was no significant change in number of neurons in CA3 zone of hippocampus and molecular, pyramidal and multiform layers of cerebral cortex in ovariectomized rats fed with soy milk. The ratio of cerebral cortex neurons to hippocampal neurons had no significant changes among the experimental groups. |
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کلیدواژههای انگلیسی مقاله |
17- β estradiol,Hippocampus,Neuron,Rat,Soy milk |
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نویسندگان مقاله |
بهرخ مرزبان عباس آبادی | marzban abbasabadi department of basic veterinary sciences, faculty of veterinary medicine, amol university of special modern technologies, amol, iran سازمان اصلی تایید شده: دانشگاه تخصصی فناوری های نوین آمل (Amol university of special modern technologies)
مینا تجلی | department of anatomical sciences, school of veterinary medicine, shiraz university, shiraz, iran سازمان اصلی تایید شده: دانشگاه شیراز (Shiraz university)
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نشانی اینترنتی |
http://vrf.iranjournals.ir/article_22172_64ac996e9de791d43531764c864f7697.pdf |
فایل مقاله |
اشکال در دسترسی به فایل - ./files/site1/rds_journals/544/article-544-279633.pdf |
کد مقاله (doi) |
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زبان مقاله منتشر شده |
en |
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