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International Journal of Infection، جلد ۱، شماره ۱، صفحات ۰-۰
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| عنوان فارسی |
Antibacterial activities of Cuminum cyminum Linn. Essential Oil Against Multi-Drug resistant Escherichia coli |
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| چکیده فارسی مقاله |
Background Development of antibiotic resistance among pathogenic bacteria motivates the researchers to search for newer antimicrobial agents. Objectives In the present study, antibacterial effects of Cuminum cyminum Linn. essential oil against multidrug resistant (MDR) Escherichia coli strains isolated from urinary tract infections were studied, using microdilution method. Materials and Methods: A total of 12 E. coli strains were isolated from urine cultures of hospitalized patients (Zabol, southeastern Iran) suffering from urinary tract infection during 2011-2012. After bacteriological confirmatory tests, minimum inhibitory concentrations (MICs) of the essential oil of C. cyminum Linn. were determined using microdilution method. Essential oil of C. cyminum Linn. was obtained by hydro-distillation and the MICs were investigated to characterize the oil antimicrobial activities. Results All of E. coli isolates were resistant to four of the antibiotics including ceftazidime (50%), cefixime (41.6%), tetracycline (75%) and erythromycin (58.3%). The highest MIC value (250 ppm) was observed against two antibiotics and the lowest (10 ppm) against one antibiotic. Conclusions C. cyminum Linn essential oil has a potent antimicrobial activity against E. coli MDR strains. Our study confirms the use of this essential oil as an antibacterial agent. However, further research will be required before its therapeutic application. |
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| کلیدواژه‌های فارسی مقاله |
Escherichia coli،Oils، Volatile،Cuminum |
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| عنوان انگلیسی |
Antibacterial activities of Cuminum cyminum Linn. Essential Oil Against Multi-Drug resistant Escherichia coli |
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| چکیده انگلیسی مقاله |
Background Development of antibiotic resistance among pathogenic bacteria motivates the researchers to search for newer antimicrobial agents. Objectives In the present study, antibacterial effects of Cuminum cyminum Linn. essential oil against multidrug resistant (MDR) Escherichia coli strains isolated from urinary tract infections were studied, using microdilution method. Materials and Methods: A total of 12 E. coli strains were isolated from urine cultures of hospitalized patients (Zabol, southeastern Iran) suffering from urinary tract infection during 2011-2012. After bacteriological confirmatory tests, minimum inhibitory concentrations (MICs) of the essential oil of C. cyminum Linn. were determined using microdilution method. Essential oil of C. cyminum Linn. was obtained by hydro-distillation and the MICs were investigated to characterize the oil antimicrobial activities. Results All of E. coli isolates were resistant to four of the antibiotics including ceftazidime (50%), cefixime (41.6%), tetracycline (75%) and erythromycin (58.3%). The highest MIC value (250 ppm) was observed against two antibiotics and the lowest (10 ppm) against one antibiotic. Conclusions C. cyminum Linn essential oil has a potent antimicrobial activity against E. coli MDR strains. Our study confirms the use of this essential oil as an antibacterial agent. However, further research will be required before its therapeutic application. |
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| کلیدواژه‌های انگلیسی مقاله |
Escherichia coli,Oils, Volatile,Cuminum |
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| نویسندگان مقاله |
محمد بکاییان | mohammad bokaeian
infectious disease and tropical medicine research center, zahedan university of medical scienes, zahedan, ir iran
yasub شیری | yasub shiri
department of agronomy and plant breeding, agriculture research center, zabol university, zabol, ir iran
سازمان اصلی تایید شده: دانشگاه زابل (Zabol university)
صفورا بزی | saphora bazi
department of biology, faculty of sciences, payam nour university, zabol, ir iran
سعیده سعیدی | saeide saeidi
department of biology, faculty of sciences, science and research branch, islamic azad university, kerman, ir iran; department of biology, faculty of sciences, science and research branch, islamic azad university, kerman, ir iran. tel 98-9153495398, fax 98-5422240696
سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)
زهرا صحی | zahra sahi
department of biology, faculty of sciences, science and research branch, islamic azad university, kerman, ir iran
سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)
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| نشانی اینترنتی |
http://www.intjinfection.com/index.php?page=article&article_id=18739 |
| فایل مقاله |
اشکال در دسترسی به فایل - ./files/site1/rds_journals/1791/article-1791-276810.pdf |
| کد مقاله (doi) |
10.17795/iji-18739 |
| زبان مقاله منتشر شده |
fa |
| موضوعات مقاله منتشر شده |
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| نوع مقاله منتشر شده |
research-article |
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