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Journal of Dentistry, Shiraz University of Medical Sciences، جلد ۲۴، شماره ۲، صفحات ۲۵۶-۲۶۱
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عنوان انگلیسی Rosai Dorfman Disease in Mandible: A Rare Case Report
چکیده انگلیسی مقاله Rosai Dorfman disease is generally defined as a massive bilateral painless cervical lymphadenopathy accompanied with both fever and leukocytosis with neutrophilia. Additionally, it may possibly be associated with polyclonal hypergammaglobulinemia, reversal of CD4/CD8 ratio, the elevated erythrocyte sedimentation rate (ESR), microcytic anemia, and thrombocytosis. Rosai-Dorfman disease is known as a benign self-limiting disease, so no treatment is required in many cases, although it causes death in some cases by involving vital organs like kidney. The treatment is required when there is a life-threatening situation such as airway obstruction or involvement of vital organs such as kidney, liver, and lower respiratory tract. The required treatment choices include steroid therapy, chemotherapy, radiotherapy, and surgery. Surgical treatment is performed for bulk removal to resolve the obstruction caused by the mass as well as taking biopsy for the definite histopathologic diagnosis of disease. A 26-year-old man was referred to oral and maxillofacial surgery (OMFS) clinic of Taleghani hospital with chief complaints of pain and swelling of left submandibular space. According to the patient himself, the swelling had been started three months earlier. After rejecting dental source of the lesion, we decided to remove the mass by excisional biopsy concerning the patient’s discomfort. Histopathology report verified Rosai Dorfman disease as definite diagnosis of the mass.
کلیدواژه‌های انگلیسی مقاله Rosai-Dorfman, RDD, Rosai Dorfman disease, SHML, Sinus histiocytosis, Hematologic Disease, Pathology, Surgery
نویسندگان مقاله Hassan Mirmohammad Sadeghi |
Dept. of Oral and Maxillofacial Surgery, Shahid Beheshti University of Medical Sciences, School of Dentistry, Tehran, Iran.

Roozbeh Azadi |
Student of Dentistry, Shahid Beheshti University of Medical Sciences, School of Dentistry Tehran, Iran.

Mehrdad Dehghanpour Barouj |
Dept. of Oral and Maxillofacial Surgery, Shahid Beheshti University of Medical Sciences, School of Dentistry, Tehran, Iran.

نشانی اینترنتی https://dentjods.sums.ac.ir/article_48871_7bad7e552962c08232c6521beb6ef8f7.pdf
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