این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Iranian Journal of Basic Medical Sciences، جلد ۲۶، شماره ۶، صفحات ۶۱۷-۶۲۷
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Anti-inflammatory, immunomodulatory and anti-oxidant effects of Ocimum basilicum L. and its main constituents: A review
چکیده انگلیسی مقاله Ocimum basilicum L. (O. basilicum) is an ornamental and therapeutic plant with various pharmacological effects and medical applications. In this article, detailed information on the anti-oxidant, immunomodulatory, and anti-inflammatory properties of O. basilicum and its main constituents was provided. The literature survey of the different databases until the end of November 2021 was explored on the immunomodulatory, anti-inflammatory and anti-oxidant effects of the herb and its constituents. The plant and its constituents showed diverse pharmacological effects including immunomodulatory, anti-inflammatory and anti-oxidant properties by improving of the inflammatory mediators including interleukin (IL)-10, IL-4, tumor necrosis factor-alpha (TNF-α), interferon gamma (IFN-γ), nitric oxide (NO), serum levels of IFN-γ, IL10 and IL-4, IgG, IgM and phospholipase A2 (PLA2), immunoglobulin E (IgE), total protein (TP), oxidant and anti-oxidant markers. O. basilicum and its main constituents therefore, could be effective on the treatment of diseases associated with inflammation, immune dysregulation and oxidative stress. The present review article provides readers with organized information about the anti-oxidant, immunomodulatory, and anti-inflammatory properties of O. basilicum.
کلیدواژه‌های انگلیسی مقاله Anti-Oxidants, Basil extract, Inflammation, Immunomodulation, Ocimum basilicum
نویسندگان مقاله | Elaheh Kamelnia
Department of Biology, Faculty of Science, Science and Research Branch, Islamic Azad University, Tehran, Iran


| Reza Mohebbati
Department of Physiology, Faculty of Medicine, Gonabad University of Medical Sciences, Gonabad, Iran|Applied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran


| Reyhane Kamelnia
Institute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran


| Hesham El-Seedi
Pharmacognosy Group, Department of Pharmaceutical Biosciences, Biomedical Centre, Uppsala University, Uppsala, Sweden|International Research Center for Food Nutrition and Safety, Jiangsu University, Zhenjiang 212013, China|Department of Chemistry, Faculty of Science, Menoufia University, 32512 Shebin El-Kom, Egypt


| Mohammad Hossein Boskabady
Applied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran|Department of Physiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
نشانی اینترنتی https://ijbms.mums.ac.ir/article_22001.html
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده Review Article
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات