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Iranian Journal of Otorhinolaryngology، جلد ۳۵، شماره ۳، صفحات ۱۴۱-۱۴۶
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Evaluation of the Incidence of Pharyngocutaneous Fistula after Total Laryngectomy |
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| چکیده انگلیسی مقاله |
Introduction:Laryngeal squamous cell carcinoma is one of the most critical head and neck cancers. Total laryngectomy is one of the main options for treating laryngeal squamous cell carcinoma responsible for forming pharyngocutaneous fistula (PCF), which increases morbidity and mortality. This study aimed to determine PCF incidence and identify the factors associated with this complication.Materials and Methods:In a retrospective cohort study, 85 patients who underwent total laryngectomy at Imam Khomeini Hospital (Tehran, Iran) from 2011 to 2019 were selected as the study population. The presence/absence of PCF, weight, anemia status (Hb < 12.5 g/dl), renal dysfunction status (GFR < 90 mL/min/1.73m2), malnutrition status (Albumin < 3.5 g/dl), and marginal involvement status was extracted from postoperative medical records. The data were analyzed using SPSS ver. 26.0. Results:The overall incidence of PCF was 11.8%. The mean ±SD of the duration of hospitalization in patients with PCF was 32.40 ±14.75 days, and in patients without PCF was 16.89 ±7.05 days (P = 0.009). The mean ±SD of time to develop a fistula was 7.4 ±3.74 days. Conclusions:The statuses of anemia, malnutrition, renal dysfunction, surgical margin, history of radiotherapy, pharynx closure, gender, and age were unrelated to the incidence of PCF. Further studies with a larger sample size are recommended. |
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| کلیدواژه‌های انگلیسی مقاله |
Pharyngocutaneous fistula, Laryngectomy, incidence, Risk factors |
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| نویسندگان مقاله |
| Maziar Motiee Langroudi
Department of Otorhinolaryngology, Tehran University of Medical Sciences, Tehran, Iran.
| Mehrdad Jafari
Department of Otorhinolaryngology, Tehran University of Medical Sciences, Tehran, Iran.
| Roxana Safari
Department of Medicine, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
| Mehraveh Sadeghi Ivraghi
Department of Medicine, School of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran.
| Alireza Mazarei
Otorhinolaryngology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
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| نشانی اینترنتی |
https://ijorl.mums.ac.ir/article_22267.html |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
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| نوع مقاله منتشر شده |
Original |
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