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Journal of Reproduction and Infertility، جلد ۲۴، شماره ۲، صفحات ۱۱۷-۱۳۲
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عنوان فارسی |
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چکیده فارسی مقاله |
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کلیدواژههای فارسی مقاله |
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عنوان انگلیسی |
Comparison of Cumulative Live Birth Rate (CLBR) According to Patient Oriented Strategies Encompassing Individualized Oocyte Number (POSEIDON) Stratification Among Low Prognosis Women Undergoing IVF-ICSI Cycles |
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چکیده انگلیسی مقاله |
Background: The purpose of the current study was to evaluate patient-oriented strategies encompassing individualized oocyte number (POSEIDON) criteria, validate stratification of low prognosis women, and prognosticate their reproductive potential in terms of cumulative live birth rate (CLBR) in Indian women. Methods: Out of 4048 women who underwent IVF/ICSI, 3287 women met the criteria for final evaluation of CLBR. They criteria were divided into (a) group 1a as cases with < 4 oocytes retrieved and 1b with 4-9 oocytes retrieved; (b) group 2a as cases with < 4 oocytes retrieved and 2b with 4-9 oocytes retrieved; (c) group 3 (< 35 years, AMH < 1.2 ng/ml, AFC < 5); and (d) group 4 (≥35 years, AMH < 1.2 ng/ml, AFC < 5). Non-POSEIDON group was sub-divided into normo-responders (10-20 oocytes) and hyper-responder (>20 oocytes). Results: Overall CLBR was two-fold lower in POSEIDON group as compared to non-POSEIDON group (p< 0.001). For every one-year increase in the age, the odds of CLBR decreased by 4% (OR 0.96, CI 0.93-0.99) in POSEIDON group and by 5% (OR 0.95, CI 0.92-0.98) in non-POSEIDON group. For every unit increase in number of oocytes retrieved, the odds of CLBR increased by 1.22 times (OR1.22, CI 1.16-1.28) in POSEIDON group and by 1.08 times (OR 1.08, CI 1.05-1.11) in non-POSEIDON group. Among POSEIDON groups, the highest values in CLBR belonged to group 1b followed by 3, 2b, 4, 1a, and 2a. Conclusion: POSEIDON stratification of low-prognosis women undergoing IVF may be considered valid to prognosticate and counsel women undergoing IVF. Prospective studies will strengthen its validity among different ethnic populations. |
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کلیدواژههای انگلیسی مقاله |
Cumulative live birth rate, Infertility, IVF, Low prognosis women, POSEIDON criteria |
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نویسندگان مقاله |
| Reeta Bansiwal Department of Obstetrics and Gynaecology, All India Institute of Medical Sciences (AIIMS), New Delhi, India
| Reeta Mahey Department of Obstetrics and Gynaecology, All India Institute of Medical Sciences (AIIMS), New Delhi, India
| Neena Malhotra Department of Obstetrics and Gynaecology, All India Institute of Medical Sciences (AIIMS), New Delhi, India
| Neeta Singh Department of Obstetrics and Gynaecology, All India Institute of Medical Sciences (AIIMS), New Delhi, India
| Monika Saini Department of Obstetrics and Gynaecology, All India Institute of Medical Sciences (AIIMS), New Delhi, India
| Ashok Bhatt Department of Obstetrics and Gynaecology, All India Institute of Medical Sciences (AIIMS), New Delhi, India
| Nilima Nilima Department of Biostatistics, All India Institute of Medical Sciences (AIIMS), New Delhi, India
| Kalaivani Mani Department of Biostatistics, All India Institute of Medical Sciences (AIIMS), New Delhi, India
| Rohitha Cheluvaraju Department of Obstetrics and Gynaecology, All India Institute of Medical Sciences (AIIMS), New Delhi, India
| Monika Rajput Department of Obstetrics and Gynaecology, All India Institute of Medical Sciences (AIIMS), New Delhi, India
| Neerja Bhatla Department of Obstetrics and Gynaecology, All India Institute of Medical Sciences (AIIMS), New Delhi, India
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نشانی اینترنتی |
https://www.jri.ir/article/140186 |
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