|
|
Transport Phenomena in Nano and Micro Scales، جلد ۹، شماره ۱، صفحات ۴۸-۶۲
|
|
|
| عنوان فارسی |
|
|
| چکیده فارسی مقاله |
|
|
| کلیدواژه‌های فارسی مقاله |
|
|
| عنوان انگلیسی |
Cancer cell separation using passive mechanisms: a review |
|
| چکیده انگلیسی مقاله |
The separation of micron-sized particles and their sorting is a critical issue in diagnosing cancer and biological analyses. For fast and accurate separation and sorting of circulating tumor cells (CTCs), various methods have been presented so far. CTCs which are responsible for cancer metastasis have the potential to provide significant prognostic and diagnostic values. In this paper, some procedures for the separation of CTCs are studied which are generally based on passive methods. These methods use the interaction between particles, flow field, and channel structure. In this study, various designs in connection with passive methods for separating and sorting CTCs are discussed, including filter/deformation, Pinched Flow Fractionation (PFF), Deterministic Lateral Displacement (DLD), inertia and Dean flow fractionation, tunable microfluidic systems, Hybrid microfluidics, and Carpet microfluidic chip technology. Overall, a list of challenges for the micro-fluidic-based cancer cell separation technologies needs to be dealt with to make them more applicable, useful, and ultimately more mature, from lab-oriented researches to real-world applications. It is suggested to perform numerical simulations by considering real shapes of rare cells. Besides, the impact of cell deformability, non-Newtonian impacts, and stretchable channels should be assessed in numerical examinations. |
|
| کلیدواژه‌های انگلیسی مقاله |
Cell separation, CTCs, Passive method, Microfluidics |
|
| نویسندگان مقاله |
Morteza Bayareh |
Department of Mechanical Engineering
Roya Mohammadali |
Department of Mechanical Engineering
Azam Usefian |
Department of Electrical Engineering, École de Technologie Supérieure (ÉTS), Canada
|
|
| نشانی اینترنتی |
https://chal.usb.ac.ir/article_6811_0a43767a2c42ce964dbc6a332233179d.pdf |
| فایل مقاله |
فایلی برای مقاله ذخیره نشده است |
| کد مقاله (doi) |
|
| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
|
| نوع مقاله منتشر شده |
|
|
|
|
برگشت به:
صفحه اول پایگاه |
نسخه مرتبط |
نشریه مرتبط |
فهرست نشریات
|