Nutrition and Food Sciences Research، جلد ۸، شماره ۱، صفحات ۱۱-۱۹

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عنوان انگلیسی Effects of a Single Session of Eccentric or Concentric Resistance Exercise on Relative Expression of BDNF, PAX7 and IGF-1 in Young Men
چکیده انگلیسی مقاله Background and Objectives: The aim of the present study was to investigate effectsof a single sessionof eccentric or concentric resistance exercise on relative expression of BDNF, PAX7 and IGF-1 in healthy participants. Materials and Methods: In a field trial, ten healthy young men were randomly assigned into two equal groupsof concentric and eccentric contractions. Isokinetic contraction protocols included eccentric and concentric knee extensions with maximum power. The torques assigned were similar in the two groups. At the beginning and end ofthe exercise, biopsies of the lateral broad muscle tissue were collectedto assess relative expression of BDNF, PAX7 and IGF-1. Results: Statistically significant increases were seen in BDNF and PAX7 expression rates of the concentric exercise group (p= 0.021 and p= 0.014, respectively). Results showed that IGF-1 protein significantly increased after concentric and eccentric exercises(p= 0.005 and p= 0.022, respectively). In eccentric exercise group, BDNF and PAX7 expression rates increasedsignificantly (p=0.034 and p= 0.034, respectively). Conclusions: Based on the findings, a single session of eccentric and concentric exercise changes factors involved in skeletal muscle strength and hypertrophy. In addition, these changes were totally more in eccentric contraction group, compared to concentric contraction group. It can be recommended to focus further on eccentric exercisesto increase hypertrophy and muscle strength.Furthermore, these findingscan be used to prevent obesity and type 2 diabetes.
کلیدواژه‌های انگلیسی مقاله Muscular contractions, Metaboliceffects, exercise modes, hypertrophy, Satellite cells

نویسندگان مقاله | Mehrnaz Ghanizadeh
PhD Student, Department of Exercise Physiology, Islamic Azad University, Central Tehran Branch, Tehran, Iran


| Mohammad Ali Azarbayjani
Department of Exercise Physiology, Islamic Azad University, Central Tehran Branch, Tehran, Iran


| Maghsoud Peeri
Department of Sports Physiology, Islamic Azad University, Central Tehran Branch, Tehran, Iran


| Hassan Matin Homaeee
Department of Exercise Physiology, Islamic Azad University, Central Tehran Branch, Tehran, Iran



نشانی اینترنتی http://nfsr.sbmu.ac.ir/browse.php?a_code=A-10-903-1&slc_lang=en&sid=1
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