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Middle East Journal of Digestive Diseases، جلد ۱۳، شماره ۲، صفحات ۱۲۱-۱۳۰
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عنوان انگلیسی Different Clinical Features of Celiac Disease in Children, Adolescents, and Adults; a Cross-sectional Study
چکیده انگلیسی مقاله BACKGROUND: Celiac disease is a common disorder but there are few studies comparing the clinical features of the disease in adults, adolescents and children. METHODS: Demographic and clinical characteristics of all patients with celiac disease referred to the Celiac Clinic were evaluated and compared in different age groups. RESULTS: Of 3416 participants, 473 patients were included. 302(63.8%) were women and 171(36.2%) were men. Overall, 325(68.7%) and 411 (86.9%) patients had gastrointestinal (GI) and non-GI manifestations, respectively. The most common symptom in adults was psychiatric problems (66.5%), while abdominal discomfort was the most common symptom in adolescents (45.2%) and children (53.8%). According to age groups, GI manifestations were seen in 79 (66.4%), 119 (59.8%), and 127 (81.9%) children, adolescents, and adults, respectively. Adults had significantly more GI manifestations than the other groups (PR 1.167; 95% CI: 1.094-1.244; p < 0.001). Non-GI manifestations were seen in 90 (75.6%), 174 (87.4%), and 147 (94.8%) children, adolescents, and adults, respectively. Adults had significantly more non-GI manifestations than the other groups (PR 1.112; 95% CI: 1.060-1.168; p < 0.001). CONCLUSIONS: Our study showed that there were significant differences in the clinical features of celiac disease between the different age groups. Considering these results may help plan for future studies.
کلیدواژه‌های انگلیسی مقاله Celiac disease, Children, Adolescents, Adults, Southern Iran, Prevalence
نویسندگان مقاله | Ramin Niknam
MPH Department, Shiraz University of Medical Sciences, Shiraz, Iran


| Alireza Salehi
MPH Department, Shiraz University of Medical Sciences, Shiraz, Iran


| Hossein Molavi Vardanjani
Gastroenterohepatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran


| Mohammad Reza Fattahi
Gastroenterohepatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran


| Seyed-Mohsen Dehghani
Neonatal Research Center, Shiraz University of Medical Sciences, Shiraz, Iran


| Nasser Honar
Gastroenterohepatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran


| Mahmood Haghighat
Gastroenterohepatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran


| Mohammad-Hadi Imanieh


نشانی اینترنتی http://mejdd.org/index.php/mejdd/article/view/2299
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