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Nanomedicine Journal، جلد ۸، شماره ۳، صفحات ۱۵۶-۱۶۵
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عنوان انگلیسی Exosomes as delivery tools in cancer therapy: Future perspectives
چکیده انگلیسی مقاله Exosomes, which are one of the extracellular vesicles, are considered necessary tools of intracellular communication that abundant in our body in physiological and pathological conditions with a diameter of 30-150 nm. The nanotubes, dendrimeric, metallic, nanoparticles have been used in the medical area. However, these nano-based systems are lack of standardized manufacturing methods and therefore, it has toxic effects on cells. The delivery methods of growth factors, exosomes, cells, and engineered tissues have notably advanced in the medical area. The fact that they contain bioactive molecules such as protein, lipid, RNA and DNA revealed that these structures may play an important role in the treatment of cancer. Here, we review work on the contribution exosomal mediated cancer treatment in two main topics as exogenous molecule carrier and self-use. We also emphasize the development of exosome-based systems by referring to the advantages and disadvantages of using exosomes and future perspectives in cancer therapy.
کلیدواژه‌های انگلیسی مقاله Advantages, Cancer Treatment, Cancer diagnosis, Disadvantages Exosome, Nanoparticle
نویسندگان مقاله | Fatma Kubra Ata
Department of Genetics and Bioengineering, Kirsehir Ahi Evran University, TR-40100 Kirsehir, Turkey


| Serap Yalcin
Department of Molecular Biology and Genetics, Kirsehir Ahi Evran University, TR-40100 Kirsehir, Turkey
نشانی اینترنتی https://nmj.mums.ac.ir/article_18164.html
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Review Paper
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