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Caspian Journal of Internal Medicine، جلد ۱۱، شماره Covid ۱۹ Supplement ۱، صفحات ۵۲۷-۵۳۰
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عنوان انگلیسی Diagnostic value of chest CT in Iranian patients with suspected COVID-19
چکیده انگلیسی مقاله Background: In the current COVID-19 pandemic, there is a rising need for a rapid and reliable diagnostic tool. We hypothesized that chest computed tomography (CT) can be a potential alternative for reverse transcription-polymerase chain reaction (RT-PCR). The aim of this study was to compare the diagnostic value of chest CT and RT-PCR in Iranian patients with suspected COVID-19. Methods: In a retrospective, single-center case series, 568 consecutive hospitalized or outpatient patients with suspected COVID-19 underwent chest CT and/or RT-PCR testing at Imam Reza Hospital, the tertiary teaching hospital of Tabriz University of Medical Sciences in Iran, from February 21 and March 28, 2020. Results: The sensitivity of chest CT for signifying COVID-19 was 64% (95% CI: 56%–71%) on the basis of positive RT-PCR results as a standard method. CT imaging also had a specificity of 77% (95% CI: 73%–81%), positive predictive value of 35% (95% CI: 0.31–0.39), negative predictive value of 66% (95% CI: 0.61–0.69), positive likelihood ratio of 2.79 (95% CI: 2.26–3.46), and negative likelihood ratio of 0.47 (95% CI: 0.38–0.57). Conclusion: Chest CT had higher specificity than RT-PCR in the diagnosis of COVID-19, . Therefore, it can play a crucial role in the early diagnosis. Similar to the previous studies, the typical CT features were patchy ground-glass opacities as well as peripheral aspects of the lungs consolidations.
کلیدواژه‌های انگلیسی مقاله Sensitivity, Specificity, Chest CT, RT-PCR, COVID-19
نویسندگان مقاله | Hanieh Salehi-Pourmehr
Research center for Evidence-Based- Medicine, Iranian EBM Center: A Joanna Briggs Institute (JBI) Center of Excellence, Tabriz University of Medical Sciences, Tabriz, Iran.


| Hojjat Pourfathi
Department of Anesthesiology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran


| Mohammad Kazem Tarzamni
Radiology Department, Medical Radiation Sciences Research Group, Imam Reza Hospital, Tabriz University of Medical Sciences, Tabriz, Iran


| Morteza Ghojazadeh
Research center for Evidence-Based- Medicine, Iranian EBM Center: A Joanna Briggs Institute (JBI) Center of Excellence, Tabriz University of Medical Sciences, Tabriz, Iran.


| Behrooz Naghili
Research Center for Infectious and Tropical Disease, Tabriz University of Medical Sciences, Tabriz, Iran


| Armin Zarrintan
Department of Radiology, Imam Reza Hospital, Tabriz University of Medical Sciences, Tabriz, Iran


| Reza Mehdipour
Research center for Evidence based- medicine, Tabriz University of Medical Sciences, 5166614756, Tabriz, Iran.


| Sakineh Hajebrahimi
Research center for Evidence-Based- Medicine, Iranian EBM Center: A Joanna Briggs Institute (JBI) Center of Excellence, Tabriz University of Medical Sciences, Tabriz, Iran.
نشانی اینترنتی http://caspjim.com/browse.php?a_code=A-10-1835-1&slc_lang=en&sid=1
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Infectious Diseases
نوع مقاله منتشر شده Original Article
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