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گوارش، جلد ۲۶، شماره ۳، صفحات ۱۶۴-۱۶۹
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عنوان انگلیسی Evaluation of Fecal Calprotectin before and after Anti-TNF Therapy in Patients with Inflammatory Bowel Syndrome
چکیده انگلیسی مقاله Background: Ulcerative colitis (UC) and Crohn’s disease are chronic relapsing disorders in which their clinical activity and treatment response are evaluated by various indices. The response rate is unpredictable, and for its evaluation, we use invasive procedures like colonoscopy and blood samples to address this issue. The current study was designed to evaluate the accuracy of fecal calprotectin before and after treatment with anti-tumor necrosis factor (TNF) in patients with inflammatory bowel disease (IBD). Materials and Methods: 46 patients with IBD who were a candidate for anti-TNF therapies were evaluated and the correlation between fecal calprotectin and disease activity before and after 5 months of treatment was studied. Result: Fecal calprotectin and disease activity after treatment with anti-TNF correlate, but before treatment, there was no correlation in the patients with UC. Conclusion: Fecal calprotectin not on its own but alongside other tests could be used for follow-up treatment.
کلیدواژه‌های انگلیسی مقاله Inflammatory Bowel Diseases, Anti-TNF, Fecal calprotectin.
نویسندگان مقاله | Naser Ebrahimi-Daryani
Gastrointestinal and Liver Diseases Research Center, Iran University of Medical science, Tehran, Iran


| Elham Pishgar
Department of Gastroenterology and Hepatology, Tehran University of Medical Sciences, Tehran, Iran


| Forough Alborzi Ivanaki
Department of Internal Medicine, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran


| Faezeh Almasi


نشانی اینترنتی http://govaresh.org/index.php/dd/article/view/2467
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Article
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