Journal of Kerman University of Medical Sciences، جلد ۲۸، شماره ۵، صفحات ۵۰۳-۵۰۵
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عنوان انگلیسی Success of Helicobacter pylori Eradication Therapy and Long Lasting Platelet Recovery in an Iranian Patient with Severe Immune Thrombocytopenia
چکیده انگلیسی مقاله Background: Helicobacter pylori is a gram-negative spirochete that usually affects the gastric mucosa and has a prevalence of more than 50% of people worldwide. It has been revealed that Helicobacter pylori infection is not only associated with chronic gastritis and peptic ulcers, but also with some hematologic disorders such as immune thrombocytopenia, iron deficiency anemia and gastric mucosa-associated lymphoid tissue lymphoma. Immune thrombocytopenia is an acquired autoimmune disorder with low platelet count due to devastation of autoantibody-coated platelets.Case report: In the present study, it was reported an Iranian patient with severe immune thrombocytopenia (platelet count 1×109/L) and Helicobacter pylori infection who achieved a long lasting platelet recovery after Helicobacter pylori eradication therapy. The patient was followed up for two years and no failure in platelet response was observed.Conclusion: Accordingly, Helicobacter pylori treatment is not only useful in immune thrombocytopenia patients with mild and moderate thrombocytopenia but also may be beneficial in severe cases of immune thrombocytopenia.
کلیدواژه‌های انگلیسی مقاله Helicobacter pylori, Purpura, Thrombocytopenic, Idiopathic, Blood Platelets
نویسندگان مقاله Esmaeil Shahabi Satlsar |
Department of Flow Cytometry, Takhte Tavous Pathobiology Laboratory, Tehran, Iran Department of Clinical Laboratory Sciences, School of Allied Medical Sciences, Guilan University of Medical Sciences, Langeroud, Iran

Maryam Sadat Hosseini |
Department of Hematology and Blood Banking, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Parisa Taheri |
Dentistery student, Islamic Azad University, Tehran dental blanch

Farahnaz Ghahremanfard |
Cancer Research Center, Semnan University of Medical Sciences, Semnan, Iran

Abbas Ali Imani Fooladi |
Applied Microbiology Research Center, Systems Biology and Prognosis Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran

Mohammad Mosleh |
Department of Hematology and Blood Banking, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Department of Flow Cytometry, Rasad Pathobiology and Genetic Laboratory, Tehran, IranTehran, Iran

نشانی اینترنتی http://jkmu.kmu.ac.ir/article_91769_3a52f28a393d149a73ae50b0191d8239.pdf
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