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Iranian Journal of Microbiology، جلد ۱۳، شماره ۳، صفحات ۲۵۷-۲۶۵
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عنوان انگلیسی Molecular epidemiology of hypervirulent Klebsiella pneumoniae: a systematic review and meta-analysis
چکیده انگلیسی مقاله Classical (CKp) and hypervirulent (hvKp) Klebsiella pneumoniae are two different circulating pathotypes. The aim of this study was to assess the prevalence, epidemiology and molecular relatedness of hvKps using a systemic review and meta-analysis. The data extracted from Medline, Embase, and Web of Science and finally 14 studies met the eligible criteria. To combine prevalence proportions of all studies, we performed the metaprop command embedded in the Meta package software. Totally, of 1814 K. pneumoniae isolates, 21.7% (394/1814) were hvKp. The molecular typing showed that all hvKp isolates were grouped into 50 different sequence types (STs) of them ST23, ST11, ST65 and ST86 were common. K1, K2 and K64 were dominant capsule serotypes that strongly related to ST23, ST65 and ST11, respectively. It seems that clonal group 23 (CG23) is associated with liver abscess and CG11 related to various clinical sources.
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نویسندگان مقاله | Rahimeh Sanikhani
Department of Bacteriology, Pasteur Institute of Iran, Tehran, Iran


| Mohammad Moeinirad
Department of Pathobiology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran


| Fereshteh Shahcheraghi
Department of Bacteriology, Pasteur Institute of Iran, Tehran, Iran


| Arezou Lari
Department of Systems Biomedicine, Pasteur Institute of Iran, Tehran, Iran


| Sepideh Fereshteh
Department of Bacteriology, Pasteur Institute of Iran, Tehran, Iran


| Amin Sepehr
Department of Bacteriology, Pasteur Institute of Iran, Tehran, Iran


| Afsaneh Salimi
Department of Bacteriology, Pasteur Institute of Iran, Tehran, Iran


| Farzad Badmasti
Department of Bacteriology, Pasteur Institute of Iran, Tehran, Iran
نشانی اینترنتی https://ijm.tums.ac.ir/index.php/ijm/article/view/2705
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