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Iranian Journal of Basic Medical Sciences، جلد ۲۳، شماره ۱۲، صفحات ۱۵۰۱-۱۵۲۶
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Withania somnifera L.: Insights into the phytochemical profile, therapeutic potential, clinical trials, and future prospective |
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| چکیده انگلیسی مقاله |
Withania somnifera L. is a multipurpose medicinal plant of family Solanaceae occurring abundantly in sub-tropical regions of the world. The folk healers used the plant to treat several diseases such as fever, cancer, asthma, diabetes, ulcer, hepatitis, eyesores, arthritis, heart problems, and hemorrhoids. The plant is famous for the anti-cancerous activity, low back pain treatment, and muscle strengthening, which may be attributed to the withanolide alkaloids. W. somnifera is also rich in numerous valued secondary metabolites such as steroids, alkaloids, flavonoids, phenolics, saponins, and glycosides. A wide range of preclinical trials such as cardioprotective, anticancer, antioxidant, antibacterial, antifungal, anti-inflammatory, hepatoprotective, anti-depressant, and hypoglycemic have been attributed to various parts of the plant. Different parts of the plant have also been evaluated for the clinical trials such as male infertility, obsessive-compulsive disorder, antianxiety, bone and muscle strengthening potential, hypolipidemic, and antidiabetic. This review focuses on folk medicinal uses, phytochemistry, pharmacological, and nutrapharmaceutical potential of the versatile plant. |
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| کلیدواژه‌های انگلیسی مقاله |
Clinical Trials, Folk medicinal uses, Nutraceuticals, Pharmacological attributes, Phytonutrients, Withanolides |
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| نویسندگان مقاله |
| Sumaira Saleem
Department of Chemistry, GC University Lahore, Lahore 54000 Pakistan
| Gulzar Muhammad
Department of Chemistry, GC University Lahore, Lahore 54000 Pakistan
| Muhammad Ajaz Hussain
Department of Chemistry, University of Sargodha, Sargodha 40100, Pakistan
| Muhammad Altaf
Department of Chemistry, GC University Lahore, Lahore 54000 Pakistan
| Syed Nasir Abbas Bukhari
Department of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Aljouf, Sakaka2014, Saudi Arabia
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| نشانی اینترنتی |
https://ijbms.mums.ac.ir/article_16781.html |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
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| نوع مقاله منتشر شده |
Review Article |
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