این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Iranian Journal of Otorhinolaryngology، جلد ۲۴، شماره ۲، صفحات ۷۹-۸۴
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عنوان انگلیسی Prophylactic Antibiotics in Otolaryngologic Surgeries: From Knowledge to Practice
چکیده انگلیسی مقاله Introduction: The management and use of antimicrobial drugs has clinical, economic, and environmental implications. In many countries, antimicrobial drugs are the most frequently prescribed therapeutic agents. Therefore, health-care policy should focus on how to establish a rational attitude toward antibiotics. This study was performed to investigate antibiotic usage as a prophylactic regimen in head and neck surgeries.  Materials and Methods: This study was a retrospective case series. Patients undergoing otolaryngology surgeries in a tertiary referral otolaryngology center were included. Members of operating room staff that were unaware of the study objectives collected patients' data using a questionnaire that contained information regarding general medical condition, disease, surgical procedure, and prophylaxis regimen and duration.   Results: Excluding infected patients, we studied 1349 patients during a four-month period who needed prophylactic antibiotics. A total of 34 different types of surgical procedures were performed. Out of the total number of patients, 503 (37.0%) received a parenteral antibiotic directly before surgery. The main antibiotics used before surgery were cephalosporins (94.9%). All of the 1349 patients were administered antibiotics after the procedure. These antibiotics where given with a mean number of doses of 4.81 (range: 1–68), and also consisted of mostly cephalosporins. Conclusion: Our results indicate that prophylactic antibiotics were being significantly misused in a tertiary referral center of a university hospital. Although teaching the principles of prophylaxis to physicians is important, we think that finding a way to bring this knowledge to practice is more important.
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نویسندگان مقاله | Minoo Khatami-Moghadam
Otorhinolaryngology Research Center, Tehran University of Medical Sciences, Amir-Alam University Hospital


| Mohammad-Taghi Khorsandi-Ashtiani
Otorhinolaryngology Research Center, Tehran University of Medical Sciences, Amir-Alam University Hospital


| Mohammad-Ali Mohagheghi
Cancer Institute, Cancer Research Center, Tehran University of Medical Sciences


| Mehrdad Hasibi
3Department of Infectious Diseases Tehran University of Medical Sciences, Tehran, Iran


| Ali Kouhi
Otorhinolaryngology Research Center, Tehran University of Medical Sciences, Amir-Alam University Hospital
نشانی اینترنتی http://ijorl.mums.ac.ir/article_208.html
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