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Iranian Journal of Otorhinolaryngology، جلد ۳۲، شماره ۴، صفحات ۱۹۷-۲۰۵
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عنوان انگلیسی Effects of Gabapentin Suspension and Rectal Acetaminophen on Postoperative Pain of Adenotonsillectomy in Children
چکیده انگلیسی مقاله Introduction: Adenotonsillectomy is the main treatment for symptomatic tonsillar hypertrophy with postoperative pain as the most common associated complication. The present study aimed to compare the efficacy of gabapentin with that reported for acetaminophen on the postoperative pain of adenotonsillectomy in children. Materials and Methods: In this double-blind clinical trial, a total of 60 children within the age range of 7-15 years undergoing adenotonsillectomy were randomly allocated to two groups of gabapentin (n=30) and acetaminophen (n=30). The first group received a 10 mg/kg dose of gabapentin suspension preoperatively and placebo (suppository) after the intubation. The second group received a 40 mg/kg dose of acetaminophen suppository and placebo suspension simultaneous with that in the case group. Using the pain scale (based on the scoreof visual analog scale, prescribed drugs, dosage as well as incidence of postoperative nausea and vomiting were recorded 0, 2, 4, 6, 12, and 24 h after the surgery. The data were analyzed using SPSS software (version 22.0). A p-value less than 0.05 was considered statistically significant. Results: There was no significant difference between the two groups considering the pain scores at 0, 2, 4, 6, 12, and 24 h after the surgery. In addition, the trend of pain intensity statistically decreased within 0 to 24 h in both acetaminophen (P
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نویسندگان مقاله | Soudabeh Haddadi
Anesthesia Research Center, Department of Anesthesiology, Alzahra Hospital,Guilan University of Medical Sciences, Rasht, Iran.


| Shideh Marzban
Anesthesia Research Center, Department of Anesthesiology, Alzahra Hospital,Guilan University of Medical Sciences, Rasht, Iran.


| Arman Parvizi
Anesthesia Research Center, Department of Anesthesiology, Alzahra Hospital,Guilan University of Medical Sciences, Rasht, Iran.


| Shadman Nemati
Rhino-Sinus, Ear, and Skull Base Diseases Research Center, Department of Otolaryngology and Head and Neck Surgery, Amiralmomenin Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.


| Aamer Chohdari
Anesthesiologist, Guilan University of Medical Sciences, Rasht, Iran.


| Zahra Atrkar Roshan
Anesthesia Research Center, Department of Anesthesiology, Alzahra Hospital,Guilan University of Medical Sciences, Rasht, Iran.


| Hedieh Ramezani
Rhino-Sinus, Ear, and Skull Base Diseases Research Center, Department of Otolaryngology and Head and Neck Surgery, Amiralmomenin Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
نشانی اینترنتی http://ijorl.mums.ac.ir/article_16027.html
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