چکیده انگلیسی مقاله |
Background: Complications of Ventolin as the most common drug used for bronchiolitis are widely known. The present study was conducted to determine the efficacy of hypertonic saline 3%, compared with Ventolin, for treatment of acute bronchiolitis in children. Methods : This double-blinded clinical trial study was conducted in Hajar Hospital, Shahrekord, Iran, from 2011 to 2012. A total of 70 patients under the age of two years with bronchiolitis were divided into two groups of 35 each. Ventolin nebulizer and hypertonic saline 3% nebulizer three times per day were administered in the first (Ventolin) and second (Hypersaline) group, respectively. The length of recovery was compared between the two groups. The data were analyzed by SPSS software (version 22) using chi-square, t-test, paired t-test, and Mann-Whitney. Results : The mean±SD length of recovery was 4.14±0.9 and 3.06±0.6 in the Ventolin and hypersaline groups, respectively. The mean duration of recovery was significantly lower in the hypersaline group (p< 0.001). Conclusion : Hypertonic saline 3% nebulizer has more pleasant therapeutic effects on acute bronchiolitis than Ventolin. Therefore, use of hypertonic saline 3% nebulizer is recommended for the treatment of acute bronchiolitis in children under two years old. |
نویسندگان مقاله |
محمد علی زمانی | mohammad ali zamani department of pediatrics, shahrekord university of medical sciences, shahrekord, iran.
مهران موحدی | mehran movahhedi department of pediatrics, shahrekord university of medical sciences, shahrekord, iran.
سید محمد کاظم نوربخش | seyyed mohammad kazem nourbakhsh department of pediatrics, tehran university of medical sciences, tehran, iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)
فروزان گنجی | forouzan ganji department of community medicine, shahrekord university of medical sciences, shahrekord, iran.
محمود رفیعیان کوپایی | mahmoud rafieian kopaei medical plants research center, shahrekord university of medical sciences, shahrekord, iran.
محمود مباشری | mahmoud mobasheri department of epidemiology, shahrekord university of medical sciences, shahrekord, iran.
ابوالفضل خوشدل | abolfazl khoshdel department of pediatrics, shahrekord university of medical sciences, shahrekord, iran.
شهرام اعتمادی فر | shahram etemadifar department of nursing, shahrekord university of medical sciences, shahrekord, iran.
مجید شیرانی | majid shirani department of surgery, shahrekord university of medical sciences, shahrekord, iran
زهرا کیوانی هفشجانی | zahra keivani hafshejani shahrekord university of medical sciences, shahrekord, iran.
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