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International Journal of Hematology-Oncology and Stem Cell Research، جلد ۱۴، شماره ۲، صفحات ۱۴۰-۱۵۰
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عنوان انگلیسی Hemoglobinopathies in Iran: An Updated Review
چکیده انگلیسی مقاله Hemoglobinopathies are the most common single gene disorders (monogenic disorders) in the world population.  Due to specific position of Iran and the presence of multi-ethnic groups in the country, there are many varieties in the molecular genetics and clinical features of hemoglobinopathies in Iran. Hemoglobinopathies include structural variants, thalassemias, and hereditary persistence of fetal hemoglobin. In this review, we look at the common structural variants in various parts of the country along with their hematological and clinical characteristics. Also, we discuss about the burden of the thalassemias in the country, different types, complications, molecular defects and therapy.
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نویسندگان مقاله | Abolfazl Nasiri
1) Students Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran 2) Department of Clinical Biochemistry, Kermanshah University of Medical Sciences, Kermanshah, Iran


| Zohreh Rahimi
1) Department of Clinical Biochemistry, Kermanshah University of Medical Sciences, Kermanshah, Iran 2) Medical Biology Research Center, Health Technology Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran


| Asad Vaisi-Raygani
1) Department of Clinical Biochemistry, Kermanshah University of Medical Sciences, Kermanshah, Iran 2) Fertility and Infertility Research Center, Health Technology Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran
نشانی اینترنتی http://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/1075
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