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Iranian Journal of Dermatology، جلد ۶، شماره ۲، صفحات ۳۴-۳۹
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Topical Trichloroacetic Acid compared with intralesional Glucantime injection in the treatment of acute wet cutaneous Leishmaniasis: An open clinical trial |
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| چکیده انگلیسی مقاله |
Background: An easy and effective topical treatment is not yet available for cutaneous leishmaniasis. Objectives: To compare the effect of topical trichloroacetic acid (TCA) and intralesional glucantime injection in the treatment of acute wet cutaneous leishmaniasis. Patients and Methods: Eighty patients with clinical diagnosis of wet cutaneous leishmaniasis in the age range of 5 to 75 years were recruited in this open clinical trial. Seven patients were withdrawn during the trial. In TCA group, 38 patients were treated three times (Every 2 weeks) with 50% TCA. In control group, 35 patients received intralesional glucantime injection weekly until healing or for a maximum of 6 weeks. All patients were followed for 3 months after last treatment. Results: After four weeks of treatment, 20 patients (52.6%) in TCA group and 17 patients (48.5%) in glucantime group, and after six weeks, 68% and 65.7% of patients in each respective group were completely cured. There was no important side effect in any groups. Conclusion: The nearly equal efficacy of TCA peeling and intralesional glucantime injection in the treatment of cutaneous leishmaniasis suggests that 50% TCA could be considered as a possible efficient therapeutic alternative in the management of this disease. |
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| کلیدواژه‌های انگلیسی مقاله |
Leishmaniasis, treatment, Clinical trial |
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| نویسندگان مقاله |
MA Nilforoosh Zadeh |
MR Reiss Zadeh |
F Jafari |
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| نشانی اینترنتی |
http://iranjd.ir/article_98471_772ddf20db7f792e87c1e45e2050a56d.pdf |
| فایل مقاله |
اشکال در دسترسی به فایل - ./files/site1/rds_journals/94/article-94-2213775.pdf |
| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
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