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Iranian Journal of Dermatology، جلد ۱۵، شماره ۴، صفحات ۱۲۷-۱۳۰
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| عنوان انگلیسی |
Efficacy of dinitrochlorobenzene in the treatment of alopecia areata |
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| چکیده انگلیسی مقاله |
Background: Various kinds of sensitizers are administrated foralopecia areata treatment. The aim of this study was to evaluatetreatment response to Dinitrochlorobenzene (DNCB) in alopeciaareata patients.Method: In this study, 117 patients were treated with DNCBunder a specific checklist. All patients were sensitized with a 2%DNCB and then treated with ascending DNCB concentrations(0.001%-2%). Response to treatment was categorized as none,mild, moderate and marked improvement.Result: Thirty three (27.5%) patients showed no response, 49(40.8%) had relapse 6 months after improvement, 29 (24.2%)had no relapse 6 months after the treatment and 6 patientswere excluded because they did not return for follow-up visits.Response to treatment in patients without eyelash and eyebrowinvolvement increased significantly (P=0.01). We did not observeany side effects except for localized dermatitis seen in 5% of thepatients.Conclusion: With respect to the suitable response to DNCBapplication and its availability, the authors suggest that DNCBbe reconsidered in alopecia areata. However, attention must bepaid to its mutagenicity.. |
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| کلیدواژه‌های انگلیسی مقاله |
Alopecia areata, contact sensitizer, dinitrochlorobenzene |
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| نویسندگان مقاله |
Zahra Fazel |
Mahnaz Banihashemi |
Mohammad-Javad Yazdanpanah |
Hadis Yousefzadeh |
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| نشانی اینترنتی |
http://iranjd.ir/article_98017_f3bc1bcf624aa5d69b456a09f7edbc12.pdf |
| فایل مقاله |
اشکال در دسترسی به فایل - ./files/site1/rds_journals/94/article-94-2213360.pdf |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
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