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Iranian Journal of Dermatology، جلد ۲۱، شماره ۴، صفحات ۱۲۸-۱۳۱
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Serum vitamin D level in patients with newly diagnosed pemphigus vulgaris |
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| چکیده انگلیسی مقاله |
Background: Pemphigus vulgaris (PV) is a rare autoimmune blistering disease of the skin and mucous membranes. Because vitamin D deficiency is associated with many immune disorders, we compared the levels of vitamin D between PV patients and healthy controls. Methods: Vitamin D level of 20 patients with PV was compared with 20 healthy individuals matched for age, gender, hours spent in the sun, body mass index (BMI) and daily vitamin D intake at the same time interval. The severity of the disease was estimated according to ABSIS score. The serum level of 25-hydroxyvitamin D (25OHD) was measured by a commercial ELISA test. Results: Vitamin D deficiency in the pemphigus vulgaris group (75%) was higher than healthy controls (45%) (P = 0.053). Mean level of vitamin D in PV patients was significantly lower than healthy controls, and was in the range of vitamin deficiency (P ? 0.05). No significant relationship was observed between the severity of the PV disease and vitamin D levels (P > 0.05). Conclusions: Based on the results of the present study, the mean level of vitamin D in patients with PV was significantly lower than healthy people. Based on our findings and given the important role of vitamin D in preventing inflammatory and autoimmune diseases, vitamin D deficiency can be considered as a factor triggering the onset of PV. |
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| کلیدواژه‌های انگلیسی مقاله |
Pemphigus vulgaris, Vitamin D, Autoimmune Disease |
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| نویسندگان مقاله |
Banihashemi Mahnaz |
Nahidi Yalda |
Meibodi Naser Tayyebi |
Jarrahi Lida |
Livani Fatemeh |
Seifnia Sahar |
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| نشانی اینترنتی |
http://iranjd.ir/article_98321_c7d6416d61d91e91b789c719f1d5dea8.pdf |
| فایل مقاله |
اشکال در دسترسی به فایل - ./files/site1/rds_journals/94/article-94-2213157.pdf |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
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