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گوارش، جلد ۲۴، شماره ۴، صفحات ۲۳۸-۲۴۰
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عنوان انگلیسی Correlation between thyroid disorders and rate of Helicobacter Pylori infection
چکیده انگلیسی مقاله Background : Hyperthyroidism and hypothyroidism are common thyroid disorders. Thyroid hormones have a great role in regulating mucosal cells and the growth of the gastrointestinal tract. In this study, we investigated the presence of Helicobacter pylori ( H. pylori) infection in various types of thyroid disorders. Materials and Methods: Our study included 297 patients whose thyroid status was identified by evaluation of thyroid hormones; triiodothyronine (T3), thyroxine (T4), and thyroid-stimulating hormone (TSH) using Roche Electrochemiluminescence (ECL). H. pylori antibodies and antigen were evaluated by enzyme-linked immunosorbent assay (ELISA) kits in all cases. Results: Hypothyroidism had a significant correlation with H. pylori infection ( p < 0.001). Hyperthyroidism was not related to H. pylori infection ( p =0.171). Also, in hypothyroidism, female sex more than male sex had a significant correlation with H. pylori infection ( p = 0.004). Conclusion: Decreasing thyroid hormones can result in dysregulation of gastric mucosal cells, therefore hypothyroidism can lead to more chance of having H. pylori infection.
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نویسندگان مقاله | Armin Mokhtariye
Department of Microbiology, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran


| Omid Pouresmaeil
Department of Medical Laboratory Sciences, Varastegan Institute for Medical Science, Mashhad, Iran


| Fatemeh Baledi
Pardis Clinical and Genetic Laboratory, Mashhad, Iran


| Sima Marzban
Department of Medical Laboratory Sciences, Varastegan Institute for Medical Science, Mashhad, Iran


| Farideh Ghavidel
Department of Medical Laboratory Sciences, Varastegan Institute for Medical Science, Mashhad, Iran


| Aref Derafsheh
Department of Medical Laboratory Sciences, Varastegan Institute for Medical Science, Mashhad, Iran


| Mahdieh Vosoughi
Department of Medical Laboratory Sciences, Varastegan Institute for Medical Science, Mashhad, Iran


| Fatemeh Keyfi


نشانی اینترنتی http://govaresh.org/index.php/dd/article/view/2151
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/141/article-141-2175828.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده Brief Report
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