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Iranian Journal of Otorhinolaryngology، جلد ۳۲، شماره ۱، صفحات ۳۵-۴۱
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عنوان انگلیسی Correlation of Serum Vitamin D Levels with Chronic Rhinosinusitis Disease Severity
چکیده انگلیسی مقاله Abstract Introduction: The present study was conducted to investigate the association between the serum vitamin D levels and severity of disease in chronic rhino sinusitis (CRS) patients. Materials and Methods: This prospective cross-sectional study was conducted on a total of 93 patients suffering from chronic rhino sinusitis with nasal polyposis (CRS w NP). Serum level of 25-hydroxyvitamin D was detected using a simple blood test. A22-item questionnaire, namely the sinonasal outcome test-22 (SNOT-22), was used to assess the subjective disease severity and patients' quality of life. In addition, the radiographic signs of the disease severity were evaluated using the Lund-Mackay Scale (LMS). Results: The mean age and serum vitamin D level of the patients were measured at 37.7±13.6 years and 24.6±16.9 ng/ml, respectively. Moreover, the mean of LMS and SNOT-22 scores were calculated at 14.2±11.2 and 40.8±17.6, respectively. There was a negative correlation between the SNOT-22 and serum levels of vitamin D (P=0.034). Similarly, LMS and serum vitamin D levels were correlated negatively (P=0.027). Furthermore, the results revealed a direct relationship between LMS and SNOT-22 (P
کلیدواژه‌های انگلیسی مقاله CRS w NP, Lund-Mackay Scale, Vitamin D, SNOT-22
نویسندگان مقاله | Vahid Zand
Department of Otolaryngology - Head and Neck Surgery, Otorhinolaryngology Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.


| Mohammadhossein Baradaranfar
Department of Otolaryngology - Head and Neck Surgery, Otorhinolaryngology Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.Medical Sciences, Yazd, Iran


| Sedighe Vaziribozorg
Department of Otolaryngology - Head and Neck Surgery, Otorhinolaryngology Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.


| Mohammad Mandegari
Department of Otolaryngology - Head and Neck Surgery, Otorhinolaryngology Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.


| Mahzad Mansourimanesh
Department of Anesthesiology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.


| Nasir Saeidieslami
Department of Otolaryngology - Head and Neck Surgery, Otorhinolaryngology Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
نشانی اینترنتی http://ijorl.mums.ac.ir/article_14223.html
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زبان مقاله منتشر شده en
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