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Bulletin of Emergency and Trauma، جلد ۶، شماره Issue ۳، صفحات ۱۹۵-۲۰۰
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عنوان انگلیسی Healing Effects of Dried and Acellular Human Amniotic Membrane and Mepitelas for Coverage of Skin Graft Donor Areas; A Randomized Clinical Trial
چکیده انگلیسی مقاله Objective: To compare the healing effects of dried and acellular human amniotic membrane and Mepitel for coverage of split-thickness graft donor site (STGDS). Methods: Twenty patients who underwent STGDS regeneration surgery in identical anatomic regions were enrolled in this randomized controlled clinical trial conducted in Hazrate Fatemeh hospital (Iran). Patients were randomly assigned in 3 groups of wound dressing; group A by Mepitel, group B AmiCare (Dried amniotic membrane) and group C OcuReg-A (Acellular amniotic membrane). Re-epithelization rate (healing time), pain sensation, scar formation and infection rate were assessed till complete healing was achieved.Results: Our results showed no significant difference between Amicare, OcuReg-A and Mepitel in the features analyzed by us including: Re-epithelization rate (healing time) P value; 0.573, Pain sensation P value: day 4 th: 0.131, day8 th: 0.93 and day 12 th: 0.365, Scar formation P value>0.05 and Infection rate.Conclusion: Our findings confirmed the safety and efficacy of AmiCare (dried amniotic membrane) and OcuReg-A (Acellular amniotic membrane) in treatment of split-thickness donor site in comparison with Mepitel as a standard wound dressing.Trial registration number: IRCT201511118177N12.
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نویسندگان مقاله Masoumeh Nouri |
1 Ph.D. of Molecular genetics, Department of Regenerative Biomedicine, Cell Science Research Center, Royan Institute, Tehran, Iran

Marzieh Ebrahimi |
Associated Professor, Department of Regenerative Biomedicine, Cell Science Research Center, Royan Institute, Tehran, Iran

Tooran Bagheri |
Burn research Center, Iran University of Medical Sciences, Tehran, Iran

Mohammad Javad Fatemi |
Professor, Burn research Center, Iran University of Medical Sciences, Tehran, Iran

Arash Najafbeygi |
Resident of plastic surgery, Hazrat Fatima Hospital, Iran University of Medical Sciences, Tehran, Iran

Shirin Araghi |
BSc of Nursing, Hazrat Fatima Hospital, Iran University of Medical Sciences, Tehran, Iran

Maryam Molaee |
BSc of Midwife, Department of Regenerative Biomedicine, Cell Science Research Center, Royan Institute, Tehran, Iran

نشانی اینترنتی http://beat.sums.ac.ir/article_44434_64b973d4574584995b096577ba8ca2b5.pdf
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