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Journal of Obstetrics, Gynecology and Cancer Research، جلد ۳، شماره ۴، صفحات ۰-۰
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عنوان انگلیسی A Case Report of Complete and Prolonged Response to Hormonal Therapy in Recurrent Metastatic Endometrial Cancer
چکیده انگلیسی مقاله Introduction: Endometrial cancer is one of the most common gynecologic malignancies in developed countries. Survival rate in metastatic endometrial adenocarcinoma recurrence is reduced, and treatment in these patients is mostly palliative.  One of the therapeutic options in the endometrial adenocarcinoma recurrence is hormone therapy. The expected response to the hormonal treatment is about 10-20%. Case presentation: This is a case report from 57-year-old woman suffering from stage IA - Grade 1 endometrial cancer, who had vaginal carcinoma recurrence with liver and pulmonary metastasis 5.5 years after the initial treatment. Due to positive hormone receptor and the pathological profile of the tumor, hormone therapy with tamoxifen and megestrol was started. The treatment evaluation revealed complete response within five months with clearance of lung and liver metastatic lesions. There is no evidence of disease and metastases in the patient's examination and imaging after 3 years of starting hormone therapy. Conclusion: In the case of well-differentiated recurrent and metastatic endometrial cancer, good response to the hormone therapy by the least complications might be achieved.
کلیدواژه‌های انگلیسی مقاله Endometrial neoplasms, Recurrence, Endocrine therapy
نویسندگان مقاله | Nafiseh Faghih
Gyneco-oncology Fellowship, Obstetrics & gynecology Ward, Emam Hosein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran


| Maliheh Arab
professor of Gyneco-oncology, Obstetrics & gynecology Ward, Emam Hosein Hospital, Shahid Beheshti University of Medical Sciences, Madani Street, Tehran, Iran
نشانی اینترنتی http://jogcr.com/browse.php?a_code=A-10-78-1&slc_lang=en&sid=1
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Gynecology Oncology
نوع مقاله منتشر شده گزارش موردی
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