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Journal of Kerman University of Medical Sciences، جلد ۲۶، شماره ۱، صفحات ۴۳-۵۴
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| عنوان فارسی |
مکمل با امگا ۳ و ویتامین E و روی و ویتامین C در مولفه های سندرم متابولیک در زنان یائسه مبتلا به دیابت نوع ۲ |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Supplementation with omega-3 plus vitamin E and zinc plus vitamin C on metabolic syndrome components in postmenopausal women with type 2 diabetes |
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| چکیده انگلیسی مقاله |
Background: The aim of this study was to find the influence of supplementation with omega-3 plus vitamin E and vitamin C plus zinc on metabolic syndrome components. Methods: In a double-blind controlled clinical trial, 75 diabetic postmenopausal women were randomly assigned to one of the three therapeutic groups of daily supplementation of 1.8g omega-3 plus 400mg vitamin E (group A), 5mg zinc plus 300mg vitamin C (group B), or placebo (group C) for 12 weeks and the results were evaluated. Results: One-way repeated measures ANOVA showed that systolic and diastolic blood pressure and waist circumference showed significant difference before and after the intervention (P= 0.0001, 0.001, and 0.045, respectively). Results of Univariate ANOVA showed that the level of plasma fasting blood sugar (FBS) and HDL-cholesterol significantly increased (P=0.01 and P=0.03, respectively) in patients who had been diagnosed as diabetic ≤7 years in group B. The plasma TG concentration significantly decreased (P=0.007) in patients who had been diagnosed as diabetic ≤7 years in group A. Systolic and diastolic BP significantly decreased (P=0.005 and P=0.04, respectively) in patients who had been diagnosed as diabetic ≤7 years in group A. The most effectiveness of nutraceutical supplementation was on patients that had been diagnosed as diabetic ≤7 years. Plasma TG and systolic BP decreased with omega-3 plus vitamin E; however, plasma FBS and HDL- cholesterol increased with zinc plus vitamin C supplementation. Conclusion: Several factors, such as duration of diabetes, age, gender, pathophysiology status, genetic, and other anthropometric characteristics may influence the effectiveness of supplementation. |
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| کلیدواژه‌های انگلیسی مقاله |
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| نویسندگان مقاله |
Mohammad Reza Mahmoodi |
Physiology Research Center, Institute of Basic and Clinical Physiology & Nutrition Department, School of Health, Kerman University of Medical Sciences. Kerman, Iran
Yadollah Mehrabi |
Department of Health and Social Medicine, School of Medicine, Shaheed Beheshti University of Medical Sciences. Tehran, Iran
Masoud Kimiagar |
Human Nutrition & Diet Therapy Department, School of Nutrition and Food Technology, Shaheed Beheshti University of Medical Sciences. Tehran, Iran
Asadollah Rajab |
Iranian Diabetes Society, Malakotti St., Tehran, Iran
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| نشانی اینترنتی |
http://jkmu.kmu.ac.ir/article_87273_f73506d218c4a814d0b12caaf8b52ca4.pdf |
| فایل مقاله |
اشکال در دسترسی به فایل - ./files/site1/rds_journals/93/article-93-1486350.pdf |
| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
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