این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Iranian Journal of Microbiology، جلد ۹، شماره ۳، صفحات ۱۶۰-۱۶۸
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Evaluation of anti-bacterial effects of nickel nanoparticles on biofilm production by Staphylococcus epidermidis
چکیده انگلیسی مقاله Background and Objectives: Staphylococcus epidermidis produces biofilm by extracellular polysaccharides, causing bacterial adherence to different surfaces. Anti-microbial effects of nickel nanoparticles on some bacterial strains such as S. aureus and Escherichia coli have been determined in limited studies. The aim of the present study is to examine the inhibitory effect of nickel nanoparticles on biofilm formation using clinical isolates of S. epidermidis and its hemolytic effect on human red blood cells. Materials and Methods: Twenty two S. epidermidis isolates were collected and identified by standard microbiological methods. Microtiter plate method was used to determine the biofilm production in bacterial isolates . The amounts of biofilm formation by isolates in the presence of 0.01, 0.05, 0.1, and 1 mg/mL concentrations of nickel nanoparticles were measured. Hemolytic activity of different concentrations of nickel nanoparticles was measured on human RBC suspensions. Results: Twenty isolates were strong, and two isolates were moderate biofilm producers. Biofilm formation significantly decreased in the presence of 0.05, 0.1, and 1 mg/mL of nickel nanoparticles (p< 0.05). Although in the presence of 0.01 mg/mL of nickel nanoparticles, decrease in biofilm formation was observed but it was not statistically significant (p=0.448). Slight hemolytic activity was seen in the presence of nickel nanoparticles. Conclusion: In this study, the ability of biofilm production was demonstrated for all clinical isolates of S. epidermidis. On the other hand, the lowering effects of nickel nanoparticles on biofilm formation were observed.
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله | Morteza Vahedi
Department of Basic Sciences, Islamic Azad University, Urmia Branch, Urmia, Iran


| Nima Hosseini-Jazani
Department of Microbiology, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran


| Saber Yousefi
Department of Microbiology, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran


| Maryam Ghahremani
Department of Microbiology, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran
نشانی اینترنتی http://ijm.tums.ac.ir/index.php/ijm/article/view/915
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/91/article-91-1354787.pdf
کد مقاله (doi)
زبان مقاله منتشر شده
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات