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JCR 2016
جستجوی مقالات
پنجشنبه 20 آذر 1404
Iranian Journal of Microbiology
، جلد ۱۰، شماره ۶، صفحات ۳۵۴-۳۶۰
عنوان فارسی
چکیده فارسی مقاله
کلیدواژههای فارسی مقاله
عنوان انگلیسی
Quantitative analysis of Staphylococcus aureus in patients with chronic rhinosinusitis under continuous ultrasound treatment
چکیده انگلیسی مقاله
Background and Objectives: Bacterial pathogens, in particular drug resistant strains, involved in chronic rhinosinusitis may result in treatment failure. Ultrasound waves are able to destroy bacterial population in sinus cavities and can recover patients. Materials and Methods: Twelve patients with chronic sinusitis and 10 healthy controls were treated by continuous ultrasound waves. Clinical specimens were collected before and after treatment. Serial diluted specimens were cultured on blood agar, chocolate and MacConkey agar plates for bacterial isolation. Bacterial DNA was extracted and used for Staphylococcus aureus detection using quantitative PCR. Results: S. aureus was the most isolated bacterium (10 patients), which was eradicated from 8 patients after treatment. Using phenotypic methods at the beginning, 3 out of 10 healthy individuals were found to be positive. From 11 positive patients for S. aureus identified by real time qPCR, 9 showed significant reduction after treatment. In the healthy group, S. aureus was detected in 4 samples using qPCR, but they were clean at the second sampling. Conclusion: According to our phenotypic and molecular experiments, continuous ultrasound treatment effectively reduced the bacterial population in studied patients (p < 0.01). This was a hopeful basis for doing more studies with ultrasound therapy as a treatment option.
کلیدواژههای انگلیسی مقاله
نویسندگان مقاله
| Narjes Feizabadi
Department of Physiotherapy, School of Rehabilitation, Iran University of Medical Sciences, Tehran, Iran
| Javad Sarrafzadeh
Department of Physiotherapy, School of Rehabilitation, Iran University of Medical Sciences, Tehran, Iran
| Mojtaba Fathali
Surgeon and Specialist in Ear, Nose and Troat, School of Rehabilitation, Tehran University of Medical Sciences, Tehran, Iran
| Behnoosh Vasaghi-Gharamaleki
Department of Basic Sciences, School of Rehabilitation, Iran University of Medical Sciences, Tehran, Iran
| Mahdi Dadgoo
Department of Physiotherapy, School of Rehabilitation, Iran University of Medical Sciences, Tehran, Iran
| Hossein Kazemian
Clinical Microbiology Research Center, Ilam University of Medical Sciences, Ilam, Iran; Department of Medical Microbiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
| Jalil Kardan-Yamchi
Department of Medical Microbiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran; Department of Pathobiology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
| Sonia Hesam Shariati
Department of Medical Microbiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
نشانی اینترنتی
http://ijm.tums.ac.ir/index.php/ijm/article/view/1953
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اشکال در دسترسی به فایل - ./files/site1/rds_journals/91/article-91-1354723.pdf
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