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Journal of Dentistry, Shiraz University of Medical Sciences، جلد ۱۰، شماره ۴، صفحات ۳۲۲-۰
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
The Modified AgNOR Staining in Diagnosis of Benign and Malignant Salivary Gland Tumors |
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| چکیده انگلیسی مقاله |
Statement of problem: Salivary gland neoplasms show varied histological and biological characteristics, and there may be difficulty in differentiating between low grade malignancies and benign tumors of the salivary glands. Purpose: The aim of this study was to investigate the diagnostic value of modified AgNOR technique in distinguishing between benign and malignant salivary gland tumors. Materials and Method: In this cross-sectional study, 40 benign salivary gland tumors (34 pleomorphic adenoma, 6 warthin tumor), 40 malignant neoplasms (26 adenoid cystic carcinoma, 14 mucoepidermoid carcinoma) and 10 chronic sialadenitis were stained with modified AgNOR technique. AgNOR counts, variation in size and dispersion of AgNOR dots in the cells were graded and compared in benign and malignant tumors. The data were statistically analyzed by ANOVA, Tukey, t-test and Kruskal-Wallis tests. Results: The mean AgNOR counts for the benign neoplasms (1.29±0.13) were less than those for the malignant neoplasms (2.87±0.25). Variation in AgNOR size and dispersion was of a higher grade in malignancy when compared with benign neoplasms ( p < 0.05). Conclusion: Our results suggest that modified AgNOR staining is useful for distinguishing benign from malignant tumors, but variation in AgNOR size and dispersion in addition to the count should also be considered. |
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| کلیدواژه‌های انگلیسی مقاله |
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| نویسندگان مقاله |
a اندیشه تدبیر | a andisheh tadbir
dept. of oral and maxillofacial pathology, faculty of dentistry, shiraz university of medical sciences, shiraz, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی شیراز (Shiraz university of medical sciences)
mj اشرف | mj ashraf
dept. of pathology, khalili hospital, shiraz university of medical sciences, shiraz, iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی شیراز (Shiraz university of medical sciences)
ma کتابی | ma ketabi
dental student, faculty of dentistry, shiraz university of medical sciences, shiraz, iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی شیراز (Shiraz university of medical sciences)
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| نشانی اینترنتی |
http://dentjods.sums.ac.ir/index.php/JDSUMS/article/view/217 |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
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| نوع مقاله منتشر شده |
Original Article |
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