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Journal of Dentistry, Shiraz University of Medical Sciences، جلد ۱۳، شماره ۲، صفحات ۴۹-۰
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عنوان انگلیسی Comparison of Two Corticosteroids Mouthwashes in Treatment of Symptomatic Oral Lichen Planus
چکیده انگلیسی مقاله Statement of Problem: Oral Lichen Planus (OLP) is a common chronic inflam-matory mucocutaneous disease and has different types. If they are symptomatic, they must be treated. Corticosteroid, especially in topical form, is commonly used. Purpose: The purpose of this study was to compare the therapeutic effects of two corticosteroid mouthwashes on treatment of symptomatic OLP. Materials and Method: The participants of this single-blind study were 44 symptomatic OLP patients. They included 27 females and 17 males. They were randomly divided into two groups and were given drug A (Dexamethasone 0.1%) or B (Triamcinolone acetonide 0.2%) for four weeks. Extension of lesions (mm 2 ) and severity of symptoms (based on Visual Analogue Scale) were recorded before and after treatment (weeks 1, 2, 4). Finally, SPSS 12 was used and Man-Whitney test was run to analyze the data. Results: In both groups extension of lesions and burning sensation decreased significantly during the four weeks of treatment. There was no statistically significant difference between the two groups. However, Dexamethasone 0.1% was more efficacious, in the fourth week, in reducing the size of lesions than Triamcinolone acetonide 0.2% ( p = 0.02). Conclusion: Both mouth washes were useful in diminishing pain and decreasing the size of lesions. However, Dexamethasone 0.1% was recommended for treat-ment of OLP because it was more efficacious than Triamcinolone acetonide 0.2%.
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نویسندگان مقاله h احدیان | h ahadian
dept. of oral medicine and diagnosis, school of dentistry, yazd shahid sadoughi university of medical sciences, yazd, iran


mh اخوان کرباسی | mh akhavan karbassi
dept. of oral medicine and diagnosis, school of dentistry, yazd shahid sadoughi university of medical sciences, yazd, iran


ar وحیدی | ar vahidi
dept. of toxicology and pharmacology, school of pharmacy, yazd shahid sadoughi university of medical sciences, yazd, iran


f اولیا | f owlia
dept. of oral medicine and diagnosis, school of dentistry, yazd shahid sadoughi university of medical sciences, yazd, iran
نشانی اینترنتی http://dentjods.sums.ac.ir/index.php/JDSUMS/article/view/49
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Article
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