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Iranian Journal of Materials Science and Engineering، جلد ۱۶، شماره ۱، صفحات ۰-۰
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عنوان انگلیسی Hydrothermal Synthesis of Cobalt- Doped Hydroxyapatite Nanoparticles: Structure, Magnetic Behaviour, Bioactivity and Antibacterial Activity
چکیده انگلیسی مقاله This study focuses on the physical, magnetic, biological and antibacterial behaviour of cobalt-doped HAp powder samples. Pure and Cobalt- doped HAp nanoparticles were synthesized by hydrothermal method. Calcium nitrate, di- ammonium hydrogen phosphate and cobalt nitrate were used as precursor materials.  The synthesized powders were characterized using x-ray diffraction pattern (XRD), fourier transform infrared spectroscopy (FTIR), field emission scanning electron microscopy (FESEM), vibrating sample magnetometer (VSM), Raman spectroscopy as well as MTT assay and cell adhesion test. Disc diffusion method was used to investigate antibacterial activity of the samples. The results confirmed the substitution of Ca by Co ions in the HAp lattice. In addition, this substitution induced size reduction and morphology change in HAp particles. All cobalt substituted HAp powder samples displayed paramagnetic properties, as opposed to the diamagnetic behaviour observed in the pure HAp samples. In addition, these nanoparticles exhibited cell adhesion, biocompatibility and antibacterial activity against S.aureus bacteria. This study focuses on the physical, magnetic, biological and antibacterial behaviour of cobalt-doped HAp powder samples. Pure and Cobalt- doped HAp nanoparticles were synthesized by hydrothermal method. Calcium nitrate, di- ammonium hydrogen phosphate and cobalt nitrate were used as precursor materials.  The synthesized powders were characterized using x-ray diffraction pattern (XRD), fourier transform infrared spectroscopy (FTIR), field emission scanning electron microscopy (FESEM), vibrating sample magnetometer (VSM), Raman spectroscopy as well as MTT assay and cell adhesion test. Disc diffusion method was used to investigate antibacterial activity of the samples. The results confirmed the substitution of Ca by Co ions in the HAp lattice. In addition, this substitution induced size reduction and morphology change in HAp particles. All cobalt substituted HAp powder samples displayed paramagnetic properties, as opposed to the diamagnetic behaviour observed in the pure HAp samples. In addition, these nanoparticles exhibited cell adhesion, biocompatibility and antibacterial activity against S.aureus bacteria.
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نویسندگان مقاله | N. Yazdani
School of Metallurgy and Materials Engineering, Iran University of Science and Technology (IUST)


| J. Javadpour
School of Metallurgy and Materials Engineering, Iran University of Science and Technology (IUST)


| B. Eftekhari Yekta
School of Metallurgy and Materials Engineering, Iran University of Science and Technology (IUST)


| M. Hamrang
School of Metallurgy and Materials Engineering, Iran University of Science and Technology (IUST)
نشانی اینترنتی http://ijmse.iust.ac.ir/browse.php?a_code=A-10-1546-1&slc_lang=en&sid=1
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/454/article-454-1259937.pdf
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Research paper
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