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Middle East Journal of Digestive Diseases، جلد ۲، شماره ۲، صفحات ۹۱-۰
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عنوان انگلیسی Demographic, Clinical Features and Treatment Outcomes in 700 Achalasia Patients in Iran
چکیده انگلیسی مقاله Background Achalasia is the most recognized motor disorder of the esophagus.Because it is an uncommon disease, most studies have reviewed small numbers of patients. Here, we report demographic, clinical features and treatment outcomes in 700 achalasia patients. Methods In all patients, diagnosis was established based on clinical, radiological, endoscopic and manometric criteria. A questionnaire was completed for each patient and included the patient's age, gender, initial symptoms, frequency of different symptoms, presence of positive family history for achalasia, other accompanying diseases and treatment outcomes. Results In our study men were affected more than women (54.3% vs. 45.7%). Patients' mean age was about 38 years. The most frequent symptoms noted were: dysphagia to solids and liquids, active regurgitation, passive regurgitation and weight loss, respectively. Women complained of chest pain more than men (59% vs. 47.1%, p =0.04). The vast majority of our patients were treated by pneumatic dilation (PD) of the LES and in long-term follow-up, 67% were in the responder group. Females responded better than males to PD. Conclusion Dysphagia to solids is the most common symptom in patients with achalasia. Chest pain was significantly higher among women. PD is an effective treatment for achalasia with long-term efficacy in the majority of patients.
کلیدواژه‌های انگلیسی مقاله Dysphagia,Achalasia,Pneumatic Dilation
نویسندگان مقاله a حسن زاده | a hasanzadeh


جواد میکاییلی | javad mikaeli


e الهی | e elahi


n محرابی | n mehrabi


آرش اعتمادی | arash etemadi


رضا ملک زاده | reza malekzadeh


نشانی اینترنتی http://www.mejdd.org/index.php/mejdd/article/view/358
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Article
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