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Middle East Journal of Digestive Diseases، جلد ۵، شماره ۳، صفحات ۱۲۹-۰
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Probiotics and Nonalcoholic Fatty liver Disease |
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| چکیده انگلیسی مقاله |
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease worldwide, both in adults and in children. NAFLD represents a spectrum of liver diseases that range from hepatic steatosis to steatohepatitis and cirrhosis. However, NAFLD is more prevalent in overweight and obese individuals. Evidence thus far suggests that hepatic triglyceride accumulaÂtion is not always derived from obesity; gut microbiota can also play a role in the development of insulin resistance, hepatic steatosis, necroinflammation and fibrosis. On the other hand, probiotics can strengthen the intestinal wall, reducing its permeability, bacterial translocation, and endotoxemia according to animal and human studies. They can also reduce oxidative and inflammaÂtory liver damage, while improving the histological state in certain situations. This review article focuses on research that has been conducted on probiotics and NAFLD, highlighting their efficacy as a novel therapeutic option for the treatment of this condition. |
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| کلیدواژه‌های انگلیسی مقاله |
Probiotics,Nonalcoholic fatty liver,cirrhosis |
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| نویسندگان مقاله |
طناز اسلام پرست | tannaz eslamparast
ساره اقتصاد | sareh eghtesad
دکتر آزیتا حکمت دوست | azita hekmatdoost
حسین پوستچی | hossein poustchi
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| نشانی اینترنتی |
http://www.mejdd.org/index.php/mejdd/article/view/1199 |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
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| نوع مقاله منتشر شده |
Review Article |
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