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Journal of Dentistry, Shiraz University of Medical Sciences، جلد ۱۶، شماره ۳، صفحات ۲۱۴-۰
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عنوان انگلیسی Human T-Lymphotropic Virus-1 Associated with Adult T-Cell Lymphoma/ Leukemia and Generalized Expansion of Palatal and Jaw Bones: A Rare Case Report
چکیده انگلیسی مقاله Human T-lymphotropic virus-1 (HTLV-1) can cause adult T-cell leukemia/ lymphoma (ATL/L), which is a rare and aggressive type of blood cancer. Herein, we report a case of ATL/L in a middle-aged man with unusual jaw presentations. The patient presented with mandibular, maxillary and palatal bony hard expansion, accompanied by generalized tooth mobility six months prior to admission to the Department of Oral Medicine. The panoramic radiograph showed generalized rarefaction of jaw bones. After laboratory examinations and bone marrow aspiration, ATL/L was diagnosed in association with HTLV-1. The patient underwent chemotherapy. Although the majority of infections associated with HTLV-1 are asymptomatic, some patients may develop blood diseases such as ATL/L and neurological disorders, mainly HTLV-1 associated myelopathy and tropical spastic paraparesis. ATL/L is a rare hematological malignancy in oral cavity that should be included in the differential diagnosis of cases with jaw swelling or generalized demineralization. Serum levels of anti-HTLV-1 antibodies should be examined in suspicious patients, particularly in endemic regions.
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نویسندگان مقاله زهره دلیرثانی | zohreh dalirsani
dept. of oral and maxillofacial medicine, oral and maxillofacial diseases research center, dept. of oral medicine, school of dentistry, mashhad university of medical sciences, mashhad, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

عباس جوادزاده بلوری | abbas javadzade bolouri
dept. of oral and maxillofacial medicine, dept. of oral medicine, school of dentistry, mashhad university of medical sciences, mashhad, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

زهرا دلاوریان | zahra delavarian
dept. of oral and maxillofacial medicine, oral and maxillofacial diseases research center, dept. of oral medicine, school of dentistry, mashhad university of medical sciences, mashhad, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

سلما بیداد | salma bidad
oral medicine specialist, mashhad, iran.


مجید صنعت خانی | majid sanatkhani
dept. of oral and maxillofacial medicine, oral and maxillofacial diseases research center, dept. of oral medicine, school of dentistry, mashhad university of medical sciences, mashhad, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

مریم امیرچقماقی | maryam amirchaghmaghi
dept. of oral and maxillofacial medicine, oral and maxillofacial diseases research center, dept. of oral medicine, school of dentistry, mashhad university of medical sciences, mashhad, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

نشانی اینترنتی http://dentjods.sums.ac.ir/index.php/JDSUMS/article/view/1177
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Case Report
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