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JCR 2016
جستجوی مقالات
سه شنبه 13 آبان 1404
Journal of Pharmaceutical Care
، جلد ۲، شماره ۴، صفحات ۱۷۷-۱۸۲
عنوان فارسی
چکیده فارسی مقاله
کلیدواژههای فارسی مقاله
عنوان انگلیسی
Magnetic Resonance Imaging Contrast Agents: A Review of Literature
چکیده انگلیسی مقاله
Magnetic Resonance Imaging (MRI) contrast agents most commonly agents used in diagnosing different diseases. Several agents have been ever introduced with different peculiar characteristics. They vary in potency, adverse reaction and other specification, so it is important to select the proper agent in different situations. We conducted a systematic literature search in MEDLINE/PUBMED, Web of Science (ISI), Scopus, Google Scholar by using keywords “gadolinium” and “MRI contrast Medias”, “Gadofosvest”, “Gadobenate” and “Gadoxetate”. The most frequent contrast media agents made based on gadolinium (Gd). These are divided into two categories based on the structure of their chelating parts, linear agents and macrocyclic agents. All characteristics of contrast media factors, including efficiency, kinetic properties, stability, side effects and the rate of resolution are directly related to the structure of chelating part of that formulation. In vitro data has shown that the macrocyclic compounds are the most stable Gd-CA as they do not bind to serum proteins, they all possess similar and relatively low relaxivity and the prevalence of Nephrogenic Systemic Fibrosis (NSF) has decreased by increasing the use of macrocyclic agents in recent years. No cases of NSF have been recorded after the administration of any of the high-relaxivity protein interacting agents, the vascular imaging agent gadofosveset trisodium (Ablavar), the hepatic imaging agent gadoxetate meglumine (Eovist), and the multipurpose agent gadobenate dimeglumine (MultiHance). In pregnancy and lactating women, stable macrocyclic agent is recommended.
کلیدواژههای انگلیسی مقاله
نویسندگان مقاله
زهرا صحرایی | zahra sahraei
clinical pharmacy department, school of pharmacy, shahid beheshti university of medical sciences, tehran, iran.
سازمان اصلی تایید شده
: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)
مهران میراب زاده | mehran mirabzadeh
school of traditional medicine, tehran university of medical sciences, tehran, iran.
سازمان اصلی تایید شده
: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)
دانیال فدایی فولادی | daniel fadaei fouladi
drug applied research center, tabriz university of medical sciences, pashmineh building, daneshgah st, tabriz 51656-65811, iran.
سازمان اصلی تایید شده
: دانشگاه علوم پزشکی تبریز (Tabriz university of medical sciences)
ندا اسلامی | neda eslami
faculty of pharmacy, lorestan university of medical sciences, khorramabad, iran.
سازمان اصلی تایید شده
: دانشگاه علوم پزشکی لرستان (Lorestan university of medical sciences)
آزاده اشراقی | azadeh eshraghi
department of clinical pharmacy, faculty of pharmacy-international campus, iran university of medical sciences, tehran, iran.
سازمان اصلی تایید شده
: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)
نشانی اینترنتی
http://jpc.tums.ac.ir/index.php/jpc/article/view/68
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زبان مقاله منتشر شده
en
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