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Journal of Dentistry, Shiraz University of Medical Sciences، جلد ۱۹، شماره ۴، صفحات ۲۹۵-۰
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عنوان انگلیسی Comparing Serum and Salivary Levels of Vitamin D in Patients with Re-current Aphthous Stomatitis and Healthy Individuals
چکیده انگلیسی مقاله Statement of the Problem: Recurrent aphthous stomatitis (RAS) is the most prevalent ulcerative condition of the oral mucosa. Many studies have emphasized on immunologic factors as the reason of inducing RAS; however, the exact etiologic cause of RAS has not been identified yet. Vitamin D has an endocrine function and regulatory effects on the immune system. It has potential therapeutic effects on autoimmune diseases, psoriasis, and neoplasms. Vitamin D deficiency has been detected in some autoimmune diseases such as rheumatoid arteritis. Purpose: The aim of the present study was to compare the serum and salivary levels of vitamin D in patients with RAS and healthy individuals. Materials and Method: In this cross sectional study, patients with RAS, referring to the Department of Oral Medicine, Tabriz Faculty of Dentistry, were evaluated after taking medical history, clinical examinations, and completing an informed consent form. The serum and salivary vitamin D levels were compared between case (n=26) and control (n=26) groups. Results: The mean serum vitamin D levels in the case and control groups were 33.0.7±12.41 and 50.89±9.30 (ng/dL), respectively, with a statistically significant difference ( p < 0.001). On the other hand, the mean salivary vitamin D levels in the case and control groups were 17.36± 8.01 and 20.79±6.31 (ng/dL), respectively, with no statistically significant difference ( p = 0.09). In addition, the correlation between the serum and salivary levels of vitamin D was 56%, being statistically significant ( p < 0.001). Conclusion: The serum levels of vitamin D in patients with RAS were significantly less than that in healthy individuals; however, there were no significant differences in salivary vitamin D levels between patients with RAS and healthy individuals. In addition, there was a significant and positive correlation between serum and salivary levels of vitamin D in all patients.
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نویسندگان مقاله | Ayla Bahramian
Dept. of Oral Medicine, School of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.


| Parisa Falsafi
Dentist, Tabriz, Iran.


| Teymour Abbasi
Postgraduate Student, Dept. of Oral and Maxillofacial Surgery, School of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.


| Milad Ghanizadeh
Dentist, Tabriz, Iran.


| Mehdi Abedini
Periodontist, Shahrood, Iran.


| Fatemeh Kavoosi
Dept. of Periodontology, School of Dentistry, Tabriz Azad University of Medical Sciences, Tabriz, Iran.


| Maryam Koohsoltani
Dept. of Periodontology, School of Dentistry, Tabriz Azad University of Medical Sciences, Tabriz, Iran.


| Fatemeh Noorbakhsh
Dept. of Operative Dentistry, School of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.


| Fatemeh Dabbaghi Tabrizi
Otorhinolaryngologist, Fellow ship of rhinology, Firoozgar hospital, Iran University of Medical Sciences, Tehran, Iran.


| Shahin Rajaeih
Dept. of Oral and Maxillofacial Surgery, Faculty of Dentistry, Kermanshah University of Medical Sciences, Kermanshah, Iran.


| Farzad Rezaei


نشانی اینترنتی http://dentjods.sums.ac.ir/index.php/JDSUMS/article/view/1942
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/331/article-331-1057273.pdf
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Article
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