|
|
Iranian Journal of Neonatology، جلد ۷، شماره ۳، صفحات ۱۷-۲۰
|
|
|
| عنوان فارسی |
|
|
| چکیده فارسی مقاله |
|
|
| کلیدواژه‌های فارسی مقاله |
|
|
| عنوان انگلیسی |
Propranolol for infantile hemangioma: An evaluation of its efficacy and safety in Iranian infants |
|
| چکیده انگلیسی مقاله |
Background: Propranolol has been recently indicated to inhibit the rapid growth and involution of infantile hemangioma. In the present study, we investigated the efficacy and safety of propranolol in Iranian infants. Methods: A total of 30 infants with indications for medical intervention, such as large hemangiomas, wounds with or without secondary infection, or active trauma-induced bleeding, were selected. First, a total concentration of 1 mg/kg/day was orally administered to the infants; the dosage further increased (2-3 mg/kg/day) in case the infants experienced no adverse effects. Following weekly (one month after treatment) and monthly (up to six months) follow-ups, hemangioma activity score (HAS) was calculated to evaluate swelling, color of the lesion, and ulcer size. Results: In the present study, infants with the mean age of 5.33±3.50 years received therapy. Improvement was observed in the lesions of all patients, characterized by a significant decline in size, change in color, and reduction in ulcer size (P< 0.001). No serious adverse effects were recorded, except agitation which was overcome by reducing the drug concentration. Conclusion: It seems that propranolol can be considered as an efficacious and safe alternative to other pharmaceutical and surgical interventions for infantile hemangiomas in Iranian infants. |
|
| کلیدواژه‌های انگلیسی مقاله |
Hemangioma, Hemangioma activity score, Infants, Propranolol |
|
| نویسندگان مقاله |
فاطمه لیوانی | fatemeh livani
md, assistant professor of dermatology, golestan university of medical sciences, gorgan, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی گلستان (Golestan university of medical sciences)
پوران لایق | pouran layegh
md, professor of dermatology, cutaneous leishmaniasis research center, mashhad university of medical sciences, mashhad, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)
بهزاد علیزاده | behzad alizadeh
md, assistant professor of pediatric cardiac diseases, department of cardiac surgery, imam reza hospital, mashhad university of medical sciences, mashhad, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)
محمد عباسی تشنیزی | mohammad abbasi tashnizi
md, associate professor of pediatric cardiac diseases, department of cardiac surgery, imam reza hospital, mashhad university of medical sciences, mashhad, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)
مریم امین مقدم | maryam amin moghaddam
md, , cutaneous leishmaniasis research center, mashhad university of medical sciences, mashhad, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)
علی طاهریان | ali taherian
md, assistant of pathology, department of pathology, mashhad university of medical sciences, mashhad, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)
|
|
| نشانی اینترنتی |
http://ijn.mums.ac.ir/article_7648.html |
| فایل مقاله |
فایلی برای مقاله ذخیره نشده است |
| کد مقاله (doi) |
|
| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
|
| نوع مقاله منتشر شده |
تحقیقی اصیل |
|
|
|
برگشت به:
صفحه اول پایگاه |
نسخه مرتبط |
نشریه مرتبط |
فهرست نشریات
|