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Nanochemistry Research، جلد ۳، شماره ۱، صفحات ۹۲-۹۸
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| عنوان انگلیسی |
A novel binary chlorhexidine-chitosan irrigant with high permeability, and long lasting synergic antibacterial effect. |
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| چکیده انگلیسی مقاله |
Objective.Chlorhexidine gluconate (CHX) is an irrigant with a reasonable antibacterial ability and rather high permeability yet often fails to remove the smear layer. To solve this problem, CHX is upgraded through its complexion with chitosan (CS). Methods.Molar roots are split longitudinally by a rotary diamond saw. Chlorhexidine-chitosan (CHX-CS) is made by combination of CHX 2% and CS and adding Glutaraldehyde (GA) as a linker agent, followed by a freeze-drying process. Results.For the first time, CHX-CS is synthesized through linking of CHX and CS with GA. Subsequently CHX-CS is fully characterized with FT-IR (Fourier transform infrared spectroscopy), SEM (Scanning electron microscopy), DLS (dynamic light scattering), and antibacterial and water wettability tests. Significance.Ournew CHX-CS complex synergically preforms the advantages of both CHX and CS. Specifically, permeability and bactericidal effects of CHX are effectively coupled with CS smear layer removal capacity. Ease of synthesis, biocompatibility, better penetration, higher antibacterial activity, and economic benefits of this complex invite its dentistry and endodontistry applications. |
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| کلیدواژه‌های انگلیسی مقاله |
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| نویسندگان مقاله |
Shabnam Hosseini |
Department of Chemistry, Collage of Sciences, Tarbiat Modares University, Tehran, Iran
Mohammad Kassaee |
Department of Chemistry, Collage of Sciences, Tarbiat Modares University, Tehran, Iran
Seyed Hossein Elahi |
Department of Mechanical Engineering, Arak University of Technology, Arak, Iran
Behnam Bolhari |
Department of Endodontics, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran
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| نشانی اینترنتی |
http://www.nanochemres.org/article_65550_b3cdb2eb10e327bdaff00874880b8596.pdf |
| فایل مقاله |
اشکال در دسترسی به فایل - ./files/site1/rds_journals/2096/article-2096-736936.pdf |
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| زبان مقاله منتشر شده |
en |
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