Caspian Journal of Internal Medicine، جلد ۱۵، شماره ۲، صفحات ۲۱۵-۲۲۷
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عنوان انگلیسی Novel therapeutic strategy for obesity through the gut microbiota-brain axis: A review article
چکیده انگلیسی مقاله Background: The interaction between commensal bacteria and the host is essential for health and the gut microbiota-brain axis plays a vital role in this regard. Obesity as a medical problem not only affect the health of the individuals, but also the economic and social aspects of communities. The presence of any dysbiosis in the composition of the gut microbiota disrupts in the gut microbiota-brain axis, which in turn leads to an increase in appetite and then obesity. Because common treatments for obesity have several drawbacks, the use of microbiota-based therapy in addition to treatment and prevention of obesity can have other numerous benefits for the individual. In this review, we intend to investigate the relationship between obesity and the gut microbiota-brain axis as well as novel treatment strategies based on this axis with an emphasis on gut microbiota.
 
کلیدواژه‌های انگلیسی مقاله Gut–brain axis, Obesity, Gut microbiota, Probiotic, Prebiotic, Fecal Microbiota transplantation.
نویسندگان مقاله | Romina Kardan
Department of Neuroscience and Addiction Studies, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran


| Jaber Hemmati
Department of Microbiology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran


| Mohsen Nazari
Department of Microbiology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran


| Amjad Ahmadi
Department of Microbiology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran


| Babak Asghari
Department of Microbiology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran


| Mehdi Azaizi
Department of Tissue Engineering and Biomaterials, School of Advanced Medical Sciences and Technologies, Hamadan University of Medical Sciences, Hamadan, Iran


| Mansoor Khaledi
Department of Microbiology and Immunology, School of Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran


| Mohammad Reza Arabestani
Department of Microbiology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran
نشانی اینترنتی http://caspjim.com/browse.php?a_code=A-10-3031-1&slc_lang=en&sid=1
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Gastroentrology
نوع مقاله منتشر شده Review Article
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