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Avicenna Journal of Phytomedicine، جلد ۱۰، شماره ۴، صفحات ۳۹۸-۴۰۶
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Grape seed extract alleviates radiation-induced damages in human blood lymphocytes |
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| چکیده انگلیسی مقاله |
Objective: Ionizing radiation induces deleterious effects in the biological systems by producing free radicals. Grape Seed Extract (GSE) as a free radical scavenger could protect the body against the damages. Materials and Methods: In this study, 12 healthy male volunteers were divided into Groups 1, 2, 3 and 4 and received 100, 300, 600 and 1000 mg GSE, respectively. Peripheral blood samples were collected from each volunteer 15 min before, and 1, 2, and 5 hr after GSE oral administration. Blood samples were then irradiated with 150 cGy of 100 kvp X-ray (Irradiated control group, was treated with only 1.5 Gy of X-rays). Cytogenic damages were detected by micronucleus assay. Results: Results showed that irradiation significantly increased the incidence of micronuclei (p Conclusion: Consumption of GSE before undergoing radiation protects human lymphocytes against X-rays by reducing radiation-induced genotoxicity. |
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| کلیدواژه‌های انگلیسی مقاله |
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| نویسندگان مقاله |
| Reza Ghasemnezhad Targhi
Department of Radiology, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran
| Valiallah Saba
Department of Radiology, Faculty of Paramedicine, AJA University of Medical Sciences, Tehran, Iran
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| نشانی اینترنتی |
http://ajp.mums.ac.ir/article_14575.html |
| فایل مقاله |
اشکال در دسترسی به فایل - ./files/site1/rds_journals/232/article-232-2470170.pdf |
| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
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| نوع مقاله منتشر شده |
Original Research Article |
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