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Avicenna Journal of Phytomedicine، جلد ۱۰، شماره ۴، صفحات ۳۶۵-۳۷۱
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Ginger (Zingiber officinale Roscoe) extract can improve the levels of some trace elements and total homocysteine and prevent oxidative damage induced by ethanol in rat eye |
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| چکیده انگلیسی مقاله |
Objective: Acute and chronic ethanol consumption cause oxidative stress and ginger improves suchconditions. In this study, the protective effects of ginger were studied on indices of oxidative stress, total homocysteinelevel and the level of the some of the oxidative stress-associated trace elements against toxicity induced by ethanol in rat eye. Materials and Methods:Twenty-four adult male Sprague-Dawley rats were randomly allocated into four groups and treated daily for 28 days as follows: group I: control;group II: ginger (1g/kg/day ginger extract by oral gavage); group III: ethanol (4g/kg/day ethanol by oral gavage) and group IV: ginger+ethanol. At the end of the experimental period, eye tissue sera were used for determination of different parameters. Furthermore, in vitro antioxidant potential and total phenol content of ginger extract were determined. Results: In ethanol group, significant changes in oxidative stress markers and levels of homocysteine and some trace elements, compared to other groups, were observed (p Conclusion: It can be concluded that ginger extract has protective effects against toxicity induced by ethanol in the eye of male rat. |
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| کلیدواژه‌های انگلیسی مقاله |
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| نویسندگان مقاله |
| Abolfazl Akbari
Department of Physiology, School of Veterinary Medicine, Shiraz University, Shiraz, Iran
| Khadijeh Nasiri
Department of Exercise Physiology, Faculty of Sport Science, University of Mazandaran, Babolsar, Iran
| Mojtaba Heydari
Poostchi Ophthalmology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
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| نشانی اینترنتی |
http://ajp.mums.ac.ir/article_14330.html |
| فایل مقاله |
اشکال در دسترسی به فایل - ./files/site1/rds_journals/232/article-232-2470167.pdf |
| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
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| نوع مقاله منتشر شده |
Original Research Article |
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