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Middle East Journal of Cancer، جلد ۵، شماره ۳، صفحات ۱۲۹-۰
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Smoking and Histological Factors Influencing Long-term Survival of Gastric Carcinoma in Consecutive Patient Series |
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| چکیده انگلیسی مقاله |
Background : There is little information about the possible influence of lifestyle and etiologic risk factors on survival amongst patients with gastric cancer. Methods : We recruited a consecutive series of 249 patients with definite diagnosis of gastric cancer who had been hospitalized in Towhid Hospital, Sanandaj, Kurdistan Province in Western Iran during a five-year period from 2006 until 2011. Survival rate was calculated according to the Kaplan-Meier and log rank statistical methods. Cox hazard regression was used to investigate the effect of the variables and adjust for the effect of age. Results : According to univariate analysis, related variables that included age, gender, Residence, histology grade, histology type, familial history of gastrointestinal cancer and mental illness during the disease had no significant effects on survival rate variation. Significant independent factors on survival included past medical history of gastrointestinal diseases (P-value = 0.010), tobacco smoking (P-value = 0.012), and early diagnosis (P-value = 0.008). Cox-regression analysis of demographic, lifestyle and histological factors with >45 years of age as the reference revealed that patients 46-65 years of age at diagnosis (HR=0.602; 95% CI=0.250-1.44; P=0.256) and those >66 years of age (HR=1.07, 95% CI=0.46-2.50, P≤0.001) had an increased risk for disease progression and death. Conclusions : Past medical history of gastrointestinal diseases, tobacco smoking and early stage diagnosis might influence the long-term survival of patients with gastric cancer. |
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| کلیدواژه‌های انگلیسی مقاله |
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| نویسندگان مقاله |
دکتر علی دل پیشه | ali delpisheh
department of clinical epidemiology, ilam university of medical sciences, ilam, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایلام (Ilam university of medical sciences)
یوسف ویسانی | yousef veisani
student research committee, ilam university of medical sciences, ilam, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایلام (Ilam university of medical sciences)
دکتر کورش سایه میری | kourosh sayehmiri
prevention of psychosocial injuries research center, ilam university of medical sciences, ilam, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایلام (Ilam university of medical sciences)
عزت اله رحیمی | ezzatollah rahimi
liver and digestive research center, kurdistan university of medical sciences, sanandaj, iran
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| نشانی اینترنتی |
http://mejc.sums.ac.ir/index.php/mejc/article/view/127 |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
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| نوع مقاله منتشر شده |
Original Article |
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