Veterinary Research Forum، جلد ۹، شماره ۳، صفحات ۲۸۵-۲۸۸

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عنوان انگلیسی Multicentric lymphoma in a Rottweiler dog with bilateral ocular involvement: A case report
چکیده انگلیسی مقاله A 10-year-old, male Rottweilerdog was presented to Small Animal Hospital of Tehran University with a history of lethargy, anorexia, weight loss, vomiting, polyuria, polydipsia and blindness. The dog showed symptoms of depression, high body temperature (39.2 ˚C), tachypnea (40 breaths min-1) and cachexia. In ophthalmic examination, bilateral hyphema (hemmorrahge in anterior chamber of the eye) and blindness were detected. The pulse of the animal was normal (90 beats min-1) and obvious general lymphadenopathy was determined. Lymph nodes were firm, freely movable, and painless on palpation. Initial differential diagnosis of lymphoma included lymphoma, metastatic neoplasia, lymphoid hyperplasia, and lymphadenitis. In hematology and cytology tests, this case was suspected to lymphoma. Immunohistochemical staining of neoplastic lymph node revealed that nearly 20.00 – 25.00% of neoplastic cells were strongly positive for anti CD3, whereas they were negative for both CD20 and CD79a. According to the microscopic and immunohistochemical findings, a diagnosis of T cell lymphoma was made. The present report is the first case of multicentric lymphoma with ocular metastasis in a dog in Iran.
کلیدواژه‌های انگلیسی مقاله Hyphema, Lymphoma, Multicentric, Rottweiler dog

نویسندگان مقاله Hamed Mansour Lakooraj |
Department of Clinical Pathology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran

Mahmood Ahmadi-hamedani |
Department of Clinical Sciences, Faculty of Veterinary Medicine, Semnan University, Semnan, Iran

Omid Dezfoulian |
Department of Pathobiology, Faculty of Veterinary Medicine, Lorestan University, Khorramabad, Iran

Masoud Selk Ghaffari |
Department of Clinical Sciences, College of Veterinary Medicine, Karaj Branch, Islamic Azad University, Alborz, Iran


نشانی اینترنتی http://vrf.iranjournals.ir/article_32090_540fad5ae2c0f2b6b57198f9685ae074.pdf
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