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Medical Laboratory Journal، جلد ۱۰، شماره ۲، صفحات ۲۵-۳۱
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Effect of Physical and Chemical Changes on the Antimicrobial Activity of Culture Supernatant Fluid of Lactic Acid Bacteria |
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| چکیده انگلیسی مقاله |
ABSTRACT Background and Objective: Lactic acid bacteria are Gram-positive, catalase-negative, nonsporulating, either rod- or coccus-shaped bacteria that have beneficial effects on their hosts by producing antimicrobial substances such as lactic acid, hydrogen peroxide, bacteriocins and biosurfactants. Bacteriocins are antimicrobial peptides that are produced by bacteria and can inhibit the growth of other bacteria. Methods: In this experimental study, bacteriocin production by Lactobacilli as known probiotic strains was evaluated in different physicochemical conditions. Antagonistic activity was evaluated using quantitative method of Microscale Optical Density Assay (MODA). After neutralization of acid and treatment with various enzymes, temperature, pH and NaCl conditions, the antimicrobial activity of culture supernatant fluid of Lactobacillus acidophilus and L. plantarum was investigated against pathogenic Proteus. Results: The culture supernatant fluid of Lactobacilli was sensitive to proteolytic enzymes with relatively good stability to temperature. The antimicrobial activity was also present due to production of bacteriocin under different NaCl conditions (1 to 4% NaCl) and pH range of 5 to 8. Conclusion: It seems that the antimicrobial liquid of Lactobacillus strains contains bacteriocin, which shows antimicrobial effects against pathogenic strains of Proteus. To investigate further this effect, some complementary studies should be performed. |
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| کلیدواژه‌های انگلیسی مقاله |
Bacteriocins, Lactobacillus, Proteus, Physicochemical. |
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| نویسندگان مقاله |
لیلا گودرزی | leila goudarzi
department of microbiology
روحا کسری کرمانشاهی | rouha kasra kermanshahi
department of microbiology
زهرا موسوی نژاد | zahra moosavi nejad
department of microbiology
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| نشانی اینترنتی |
http://www.goums.ac.ir/mljgoums/browse.php?a_code=A-10-1-391&slc_lang=fa&sid=fa |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
تخصصی |
| نوع مقاله منتشر شده |
تحقیقی |
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